产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
山羊抗SNAP25, 生物素抗体
目录 :
MBS423684
规格 :
0.1毫克
价格 :
305美元
克隆性 :
多克隆
宿主 :
山羊
共轭标签 :
生物素
反应物种 :
人类, 小鼠, 大鼠, 狗
应用 :
免疫印迹, 免疫组化, 酶免疫法
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS423684 图像 1
Biotinylated (0.1ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer), exactly mirroring its parental non-biotinylated product. Primary incubation was 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP blocker as a substitute for skimmed milk.
产品信息
目录号 :
MBS423684
产品类型 :
抗体
产品全称 :
山羊抗SNAP25, 生物素抗体
产品简称 :
[SNAP25]
产品名称同义词 :
[Goat Anti-SNAP25 Antibody; SNAP25 antibody; synaptosome associated protein 25kDa antibody; CMS18 antibody; RIC-4 antibody; RIC4 antibody; SEC9 antibody; SNAP antibody; SNAP-25 antibody; SUP antibody; bA416N4.2 antibody; dJ1068F16.2 antibody; resistance to inhibitors of cholinesterase 4 homolog antibody; synaptosomal-associated protein, 25kDa antibody]
其他名称 :
[synaptosomal-associated protein 25 isoform SNAP25A; Synaptosomal-associated protein 25; synaptosomal-associated protein 25; synaptosome associated protein 25; Super protein; SUP; Synaptosomal-associated 25 kDa protein]
产品基因名称 :
[SNAP25]
其他基因名称 :
[SNAP25;SNAP25;SUP;RIC4;SEC9;SNAP;CMS18;RIC-4;SNAP-25;bA416N4.2;dJ1068F16.2;SNAP;SNAP-25;SUP]
UniProt数据库进入名 :
SNP25_HUMAN
克隆性 :
多克隆
宿主 :
山羊
反应物种 :
Tested: Human, Mouse, Rat. Expected from sequence similarity: Human, Mouse, Rat, Dog
序列长度 :
206
序列 :
DEANQRATKMLGSG.
纯度 :
通过硫酸铵沉淀和用免疫多肽抗原亲和层析从山羊血清中纯化得到的
形式 :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
储存稳定性 :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
检测过的应用 :
肽酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化)
应用笔记 :
Western Blot: Approx 26kDa band observed in Rat Brain lysates (calculated MW of 23.3kDa according to NP_003072.2 and NP_570824.1). See non-biotinylated parental product's datasheet for further QC data. Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: Antibody detection limit dilution 1:64000.
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Immunogen: Peptide with sequence C-DEANQRATKMLGSG., from the C Terminus of the protein sequence according to NP_003072.2; NP_570824.1. Epitope: C Terminus
其他信息2 :
Note: This antibody is expected to recognise both reported isoforms NP_003072.2 (SNAP25A) and NP_570824.1 (SNAP25B). Reported variants represent identical protein: NP_001309831.1, NP_003072.2 Reported variants represent identical protein: NP_001309834.1, NP_001309832.1, NP_001309833.1, NP_001309839.1, NP_001309836.1, NP_570824.1, NP_001309838.1, NP_001309835.1, NP_001309837.1
NCBI GI登录号 :
18765733
NCBI登录号 :
NP_003072.2
NCBI基因登录号 :
NM_003081.4
NCBI分子量 :
23,336 Da
NCBI信号通路 :
Acetylcholine Neurotransmitter Release Cycle Pathway (1268773); Disease Pathway (1268854); Dopamine Neurotransmitter Release Cycle Pathway (1268772); Effects Of Botulinum Toxin Pathway (138028); GABA Synthesis, Release, Reuptake And Degradation Pathway (1268774); Glutamate Neurotransmitter Release Cycle Pathway (1268771); Infectious Disease Pathway (1269056); Insulin Signaling Pathway (198845); Insulin Secretion Pathway (777534); Integration Of Energy Metabolism Pathway (1270101)
NCBI总结 :
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
SNAP-25: a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Part of the SNARE core complex containing SNAP25, VAMP2 and syntaxin 1A. Associates with proteins involved in vesicle docking and membrane fusion. Two alternatively spliced isoforms have been described. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 20p12-p11.2. Cellular Component: cytoplasm; cytosol; growth cone; membrane; neuron projection; plasma membrane; presynaptic membrane; SNARE complex; vesicle; voltage-gated potassium channel complex. Molecular Function: calcium-dependent protein binding; protein binding; SNAP receptor activity; syntaxin-1 binding. Biological Process: glutamate secretion; neurotransmitter secretion; regulation of insulin secretion; synaptic vesicle exocytosis; synaptic vesicle fusion to presynaptic membrane; synaptic vesicle priming. Disease: Myasthenic Syndrome, Congenital, 18
尺寸1 :
0.1毫克
价格1 :
305美元
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。