抗体

早期内涵体抗原1多克隆抗体

MBS448005

0.6毫克

300美元

多克隆

山羊

未共轭

人类, 小鼠, 大鼠, 狗

免疫印迹, 免疫细胞化学

抗体

早期内涵体抗原1多克隆抗体

[早期内涵体抗原1]

[Anti-EEA1; Early endosome antigen 1,162kD; early endosome-associated protein; endosome-associated protein p162; zinc finger FYVE domain-containing protein 2 antibody]

[early endosome antigen 1; Early endosome antigen 1; early endosome antigen 1; early endosome antigen 1, 162kD; endosome-associated protein p162; early endosome-associated protein; zinc finger FYVE domain-containing protein 2; early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2]

[早期内涵体抗原1]

[早期内涵体抗原1;早期内涵体抗原1;MST105;ZFYVE2;MSTP105;ZFYVE2]

EEA1_HUMAN

多克隆

IgG

山羊

human, rat, mouse, canine and monkey proteins.

1411

Detects a band of 180 kDa by Western blot in the following human, mouse and rat whole cell lysates.

Polyclonal antibody supplied as (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.

免疫荧光(IF), 免疫印迹(免疫印迹)

Western Blot: 1:250-1:1,000. Immunofluorescence: 1:50-1:250

Reactivity Chart

试验数据

Gene Identifier: ENSG00000102189. Immunogen: Purified recombinant peptide within residues 1,230 aa to the C-terminus of human EEA1 produced in E. coli.

Handling: The antibody solution should be gently mixed before use.

Early Endosome Antigen 1. Goat polyclonal antibody to EEA1 - early endosome marker. EEA1 is Early Endosome Antigen 1 protein that binds phospholipid vesicles containing phosphatidylinositol 3-phosphate, which is necessary for endosomal trafficking.

55770888

NP_003557.2

NM_003566.3

Q15075

162,466 Da

Endocytosis Pathway (102279); Endocytosis Pathway (102181); Immune System Pathway (106386); Innate Immune System Pathway (106387); Phagosome Pathway (153910); Phagosome Pathway (153859); Toll Like Receptor 9 (TLR9) Cascade Pathway (106397); Toll-Like Receptors Cascades Pathway (106388); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)

Function: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Subunit structure: Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. Interacts with RAB31. Interacts with ERBB2. May interact with PLEKHF2. Ref.5 Ref.6 Ref.7 Ref.8 Ref.9 Ref.10 Ref.11 Ref.12 Ref.13 Ref.17 Ref.18. Subcellular location: Cytoplasm. Early endosome membrane; Peripheral membrane protein Ref.1 Ref.7 Ref.9 Ref.13 Ref.17. Domain: The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate in membranes of early endosomes and penetrates bilayers. The FYVE domain insertion into PtdIns3P-enriched membranes is substantially increased in acidic conditions. Ref.14. Miscellaneous: Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. Sequence similarities: Contains 1 C2H2-type zinc finger.Contains 1 FYVE-type zinc finger.

0.6毫克

300美元