产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
兔抗TGF-b2抗体
目录 :
MBS462143
规格 :
0.1毫克
价格 :
350美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化
更多信息或购买 :
产品信息
目录号 :
MBS462143
产品类型 :
抗体
产品全称 :
兔抗TGF-b2抗体
产品简称 :
TGF乙2
产品名称同义词 :
兔抗TGFb2
其他名称 :
Transforming growth factor beta-2; Transforming growth factor beta-2; transforming growth factor beta-2; G-TSF; cetermin; polyergin; TGF-beta-2; OTTHUMP00000037528; OTTHUMP00000037529; BSC-1 cell growth inhibitor; glioblastoma-derived T-cell suppressor factor; transforming growth factor, beta 2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Polyergin
产品基因名称 :
TGF乙2
其他基因名称 :
TGFB2;TGFB2;MGC116892;TGF-beta2
UniProt数据库进入名 :
TGFB2_HUMAN
宿主 :
反应物种 :
人类, 小鼠, 大鼠
特异性 :
This antibody recognizes ~13 kDa of TGF-beta 2, not TGF-beta 1 and less extense of TGF-beta 3. It reacts with human, rat and mouse. The other species are not tested.
纯度 :
The Rabbit IgG is purified by Epitope affinity purification
形式 :
This affinity purified antibody is supplied in sterile Phosphate-buffered saline (pH7.2) containing antibody stabilizer.
浓度 :
Size: 100 ug/200 ul
储存稳定性 :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. Upon initial thawing, apportion into working aliquots and store at -70 degree C for up to six months. The antibodies can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
检测过的应用 :
酶联免疫吸附测定, 免疫印迹, 免疫组化
应用笔记 :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Immunohistochemistry: 2-5 ug/ml
其它信息1 :
Antigen Preparation: A synthetic peptide derived from C-terminus of human TGF-beta 2 protein.
其他信息2 :
Positive Control: Placenta. Cellular Location: Membrane and cytoplasmic
NCBI GI登录号 :
48429157
NCBI登录号 :
P61812.1
NCBI基因登录号 :
P61812
UniProt数据库登录号 :
P61812
NCBI分子量 :
~13 kDa
NCBI信号通路 :
ATF-2 Transcription Factor Network Pathway (138006); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Chronic Myeloid Leukemia Pathway (83116); Chronic Myeloid Leukemia Pathway (528); Colorectal Cancer Pathway (83106)
NCBI总结 :
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
UniProt数据库总结 :
Function: TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. Subunit structure: Homodimer; disulfide-linked. Interacts with ASPN. Ref.11. Subcellular location: Secreted. Involvement in disease: Note=A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9. Sequence similarities: Belongs to the TGF-beta family.
尺寸1 :
0.1毫克
价格1 :
350美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。