产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
β微管蛋白
目录 :
MBS470004
规格 :
0.1毫升
价格 :
170美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
产品信息
目录号 :
MBS470004
产品类型 :
抗体
产品全称 :
β微管蛋白
产品简称 :
β微管蛋白
产品名称同义词 :
微管蛋白乙
克隆性 :
单克隆
抗体亚型 :
IgG1
宿主 :
小鼠
反应物种 :
人类, 大鼠, 小鼠
特异性 :
This antibody detects a 50 kDa* protein corresponding to the molecular mass of b-Tubulin on SDS-PAGE immunoblots of purified brain tubulin, mouse brain tissue, rat PC12 cells, and human A431 and SH-SY5Y cells.
纯度 :
蛋白质A纯化
形式 :
Mouse monoclonal antibody purified with protein A chromatography is supplied in 100ml phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide.
储存稳定性 :
Store at -20 degree C. Do not aliquot. Stable for 1 year.
检测过的应用 :
酶联免疫吸附测定, 免疫印迹, 免疫细胞化学
应用笔记 :
ELISA: 1:2000. Immunocytochemistry: 1:200. Western Blot: 1:1000
其它信息1 :
Immunogen: Clone (M154) was generated from purified porcine brain tubulin.
产品描述 :
Microtubules (MTs) are cytoskeletal elements that play an essential role in cell division and cytoplasmic organization. MTs are dynamic polymers of a/b-tubulin heterodimers. At least two populations of MTs, called dynamic and stable according to their rates of turnover, are readily distinguishable in cells. The proteins associated with MTs (MAPs) are among the best-known factors that regulate MT dynamics and stability. In addition, a variety of different post-translational modifications may also regulate MT dynamics and stability. Phosphorylation is one of these modifications and it can occur on serine, threonine, and tyrosine residues in b-tubulin isoforms. Multiple kinases can phosphorylate Ser-444 at the C-terminus of bIII-tubulin in vitro. Unphosphorylated Ser-444 in bIII-tubulin is an early marker for cells of neuronal lineage, while phosphorylation of Ser-444 is upregulated after neuronal maturation and may preferentially occur in assembled MTs. By contrast, Cdk1 phosphorylation of Ser-172 in b-tubulin occurs in mitotic cells and may impair tubulin incorporation into microtubules.
产品引用 :
Fourest-Lieuvin, A. et al. (2006) Mol. Biol. Cell. 17(3):1041. Westermann, S. & Weber, K. (2003) Nat. Rev. Mol. Cell. Biol. 4:938. Fanarraga, M.L. et al. (1999) Eur. J. Neurosci. 11:517. Diaz-Nido, J. et al. (1990) J Biol. Chem. 265(23):13949.
尺寸1 :
0.1毫升
价格1 :
170美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。