抗体

抗PGE2, 兔多克隆

MBS480053

1毫升

170美元

多克隆

兔

未共轭

酶联免疫吸附测定, 放射免疫分析法, 酶免疫法

抗体

抗PGE2, 兔多克隆

PGE2

抗前列腺素E2

Prostaglandin E synthase 2; Prostaglandin E synthase 2; prostaglandin E synthase 2; GATE-binding factor 1; gamma-interferon-activated transcriptional element-binding factor 1; mPGE synthase-2; membrane-associated prostaglandin E synthase 2; membrane-associated prostaglandin E synthase-2; microsomal prostaglandin E synthase-2; prostaglandin-H(2) E-isomerase; prostaglandin E synthase 2; Membrane-associated prostaglandin E synthase-2

PGE2

PTGES2;PTGES2;GBF1;GBF-1;PGES2;C9orf15;mPGES-2;C9orf15;PGES2;mPGES-2

PGES2_HUMAN

多克隆

兔

377

Not species specific. May not exhibit utility when using in a rabbit experimental model.

Not purified

At -80 degree C. AVOID REPEATED FREEZE THAWS.

放射免疫分析法(RIA), 酶联免疫吸附测定(EIA)

RIA: 1:25 dilution. May also have utility in ELISA.

Storage Buffer: PBS; 0.1% Sodium Azide. Sensitivity: 130 pg/assay (IC50). Immunogen: Prostaglandin E2

Description: This rabbit polyclonal antibody is specific to Prostaglandin E2 and other associated pathway specific arachidonate derived molecules. This antibody is presented as antiserum.

Levine, L., Measurement of Arachidonic Acid Metabolites by. Radioimmunoassay. In: Manual of Clinical Laboratory. Immunology (3rd Edition). J.L. Fahey, H. Friedman and N.L. Rose. (eds.). Amer. Soc. Microbiol. pp. 685-691 (1986). Granstrom, E. and Lindgren, J.A., Radioimmunoassay of. Prostaglandins and Related Compounds. In: Prostaglandins:. Biology and Chemistry of Prostaglandins and Related. Eicosanoids, P.B. Curtis-Prior, (Ed.) Churchill Livingstone, New. York, pp. 115-12. 6. Powell, W.S., Rapid Extraction of Arachidonic Acid Metabolites From. Biological Samples Using Octadecylsilyl Silica. Meth. Enzymol. 86: 467-476 (1982).

73921741

Q9H7Z7.1

Q9H7Z7

41,943 Da

Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (366); C20 Prostanoid Biosynthesis Pathway (545299); C20 Prostanoid Biosynthesis Pathway (908107); Eicosanoid Synthesis Pathway (198888); IFN-gamma Pathway (138040); Metabolic Pathways (132956)

The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]

PTGES2: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Belongs to the GST superfamily. Protein type: Isomerase; EC 5.3.99.3; Lipid Metabolism - arachidonic acid; Membrane protein, integral. Chromosomal Location of Human Ortholog: 9q34.11. Cellular Component: Golgi membrane; mitochondrion; perinuclear region of cytoplasm; integral to membrane; cytosol; nucleus. Molecular Function: DNA binding; glutathione binding; electron carrier activity; lyase activity; heme binding; protein disulfide oxidoreductase activity; prostaglandin-E synthase activity. Biological Process: secretion; cell redox homeostasis; positive regulation of transcription, DNA-dependent; prostaglandin biosynthetic process

1毫升

170美元