产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
PAD6重组蛋白
目录 :
MBS515212
规格 :
0.02毫克
价格 :
270美元
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS515212 图像 1
The purity of PAD6 was determined to be >95% by densitometry. Approx. MW 100 kDa .
产品信息
目录号 :
MBS515212
产品类型 :
重组蛋白
产品全称 :
PAD6重组蛋白
产品简称 :
[PAD6]
产品名称同义词 :
[PADI6]
其他名称 :
[Homo sapiens peptidyl arginine deiminase, type VI (PADI6), mRNA; Protein-arginine deiminase type-6; protein-arginine deiminase type-6; peptidylarginine deiminase type 6; peptidyl arginine deiminase-like protein; peptidyl arginine deiminase, type VI; Peptidyl arginine deiminase-like protein; Peptidylarginine deiminase VI; hPADVI; Protein-arginine deiminase type VI]
产品基因名称 :
[PAD6]
其他基因名称 :
[PADI6;PADI6;hPADVI;hPADVI]
UniProt数据库进入名 :
PADI6_HUMAN
宿主 :
Sf9昆虫细胞
序列长度 :
2346
形式 :
Recombinant protein stored in 50mM Tris-HCI, pH 7.5, 50mM NaCI, 10 mM glutathione,0.1 mM EDTA, 0.25mM DTT, 0.01 PMSF, 25% glycerol.
浓度 :
0.1微克/微升
储存稳定性 :
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. Stability: 1 year at -70°C from date of shipment.
检测过的应用 :
免疫印迹(免疫印迹)
image1头 :
试验数据
其它信息1 :
Type: Recombinant Fusion Protein. Species: Human. Tag Information: N-terminal GST. Source Note: Recombinant full-length human PAD6 was expressed by baculovirus in Sf9 insect cells
产品种类 :
Arginine Deiminases Proteins
产品描述 :
Recombinant full-length human PAD6 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_207421. Scientific Background PAD6 or PADI6 is a member of the peptidylarginine deiminases which convert arginine residues to citru lline residues in the presence of calcium ions. The PAD family members are thought to be involved in multiple sclerosis and rheumatoid arthritis pathophysiology, and they play a role in epidermis homeostasis 1). PAD6 is essent ial for formation of a novel oocyte-restricted fibrous structure, the cytoplasmic lattices CPLs). PAD6/CPL superstru cture plays a key role in regulating microtubule-mediated organelle positioning and movement (2).
NCBI GI登录号 :
117414157
NCBI登录号 :
NP_997304.3
NCBI基因登录号 :
NM_207421
UniProt数据库登录号 :
Q6TGC4
NCBI分子量 :
100 kDa
NCBI信号通路 :
Protein Citrullination Pathway (142167); Protein Citrullination Pathway (138213)
NCBI总结 :
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]
UniProt数据库总结 :
Function: Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo . By similarity. Catalytic activity: Protein L-arginine + H2O = protein L-citrulline + NH3. Cofactor: Calcium . By similarity. Subcellular location: Cytoplasm . By similarity. Nucleus . By similarity. Tissue specificity: Ovary, testis and peripheral blood leukocytes. Ref.1. Sequence similarities: Belongs to the protein arginine deiminase family.
尺寸1 :
0.02毫克
价格1 :
270美元
尺寸2 :
0.05毫克
价格2 :
450
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。