抗体

抗小鼠CD34, 异硫氰酸荧光素(克隆MEC14.7)(大鼠IgG2a)

MBS520461

0.1毫克

230美元

单克隆

大鼠

异硫氰酸荧光素

MEC 14.7

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, 流式细胞仪, 流式细胞仪, 酶免疫法

抗体

抗小鼠CD34, 异硫氰酸荧光素(克隆MEC14.7)(大鼠IgG2a)

CD34

CD34, 异硫氰酸荧光素(克隆MEC14.7)(大鼠IgG2a);抗小鼠CD34单克隆抗体

CD34;造血祖细胞抗原CD34;造血祖细胞抗原CD34;CD34抗原;CD34分子

CD34

CD34;CD34

CD34_HUMAN

单克隆

大鼠IgG2a

MEC 14.7

大鼠

小鼠

328

CD34 (mucosialin; sialomucin) (Mouse CD34)

异硫氰酸荧光素

0.1毫克/毫升

For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Ascites, Purified, Biotin, FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.

免疫组化(免疫组化), 流式细胞仪(FC/流式细胞仪), 酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫沉淀(免疫沉淀)

Presentation: Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

progenitor cells. The antibody recognizes a neuraminidase sensitive epitope on endothelium in vivo, particularly on small vessels and neoformed capillaries and developing vascular structures in embryonal structures. The antibody reacts with hematopoietic progenitors particularly of myelomonocytic colony forming cells. It is a useful reagent for identification and characterization of capillary endothelial cells. Furthermore the antibody can be used for isolation and characterization of hematopoietic progenitor cells. This clone is suitable for use in ELISA, immunofluorescence, immunohistochemistry on frozen4 and paraffin sections2,3, Western Blot, immunoprecipitation, flow cytometry and cell separation

264769

AAB25223.1

P28906

40,716 Da

Adaptive Immune System Pathway (366160); C-MYB Transcription Factor Network Pathway (138073); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413)

The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Function: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Subcellular location: Membrane; Single-pass type I membrane protein. Tissue specificity: Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. Developmental stage: On early hematopoietic progenitor cells. Post-translational modification: Highly glycosylated.Phosphorylated on serine residues by PKC. Ref.10. Sequence similarities: Belongs to the CD34 family. Sequence caution: The sequence AAA03181.1 differs from that shown. Reason: Erroneous initiation.

0.1毫克

230美元

0.3毫克

375