抗体

肾素抗体

MBS530796

0.2毫升

515美元

单克隆

小鼠

未共轭

118

抗体

肾素抗体

肾素

单克隆肾素;抗肾素

renin; Renin; renin; renin; Angiotensinogenase

REN;REN;HNFJ2

RENI_HUMAN

单克隆

118

小鼠

No cross reaction with Human

406

小鼠和大鼠肾素

以冻干粉末状提供

Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -80 degree C for long term storage. Avoid repeated freeze/thaw cycles.

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Biological Significance: Renin, also known as an angiotensinogenase is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure.

Immunogen: Renin antibody was raised in mouse using submandibular gland renin as the immunogen.

Proteases, Inhibitors, & Enzymes

小鼠单克隆肾素抗体

190994

AAA60363.1

P00797

44,726 Da

ACE Inhibitor Pathway 198763!!Metabolism Of Angiotensinogen To Angiotensins Pathway 685555!!Metabolism Of Proteins Pathway 106230!!Peptide Hormone Metabolism Pathway 771603!!Renin-angiotensin System Pathway 83075!!Renin-angiotensin System Pathway 486

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]

0.2毫升

515美元