抗体

血管紧张素抗体

MBS531123

0.2毫升

625美元

单克隆

小鼠

nonconjugated

71505

抗体

血管紧张素抗体

血管紧张素

单克隆血管紧张素;抗血管紧张素

angiotensinogen; Angiotensinogen; angiotensinogen; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Serpin A8

AGT; AGT; ANHU; SERPINA8; SERPINA8; Ang I; Ang II; Ang III; Ang IV

ANGT_HUMAN

单克隆

71505

小鼠

485

以冻干粉末状提供

Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -80 degree C for long term storage. Avoid repeated freeze/thaw cycles.

User optimized

Biological Significance: Angiotensinogen is an a-2-globulin that is produced constitutively and released into the circulation mainly by the liver. It is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Plasma angiotensinogen levels are increased by plasma corticosteroid, estrogen, thyroid hormone, and angiotensin II levels. Angiotensinogen is also known as renin substrate.

Immunogen: Angiotensinogen antibody was raised in mouse using rat angiotensinogen as the immunogen.

Cardiac Markers

小鼠单克隆血管紧张素抗体

532198

AAA51679.1

P01019

53,154 Da

ACE Inhibitor Pathway 198763!!Adipogenesis Pathway 198832!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!G Alpha (i) Signalling Events Pathway 119550!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Metabolism Pathway 477135

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]

0.2毫升

625美元