抗体

Hemoglobin epsilon antibody

MBS531187

0.1毫克

430美元

单克隆

小鼠

未共轭

90050

抗体

Hemoglobin epsilon antibody

Hemoglobin epsilon

Monoclonal Hemoglobin epsilon; Anti-Hemoglobin epsilon; Hemoglobin

hemoglobin subunit epsilon; Hemoglobin subunit epsilon; hemoglobin subunit epsilon; hemoglobin, epsilon 1; Epsilon-globin; Hemoglobin epsilon chain

HBE1;HBE1;HBE;HBE

HBE_HUMAN

单克隆

IgG1 kappa

90050

小鼠

人类

147

Hemoglobin Epsilon antibody

PBS, pH 7.4, with 0.05% NaN3.

Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

User optimized

Biological Significance: Hemoglobin Gower-1 is found as a minor Hb in the early embryo. It disappears by the third month of pregnancy in favour of haemoglobin Gower-2 and haemaglobin Portland and then Hb F. The zeta chain has 141 amino acid residues. Synthesis of the zeta chain is deficient in cases of hydrops foetalis.

Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Hemoglobin epsilon antibody was raised in mouse using hemoglobin Gower-I (a2e2) isolated from culture fluids of the cell line K562 as the immunogen.

营养&代谢

Mouse monoclonal Hemoglobin epsilon antibody

4885393

NP_005321.1

NM_005330.3

P02100

16,203 Da

Factors Involved In Megakaryocyte Development And Platelet Production Pathway (187196); Hemostasis Pathway (106028)

The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' [provided by RefSeq, Jul 2008]

HBE1: The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin. Belongs to the globin family. Protein type: Carrier. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: hemoglobin complex; cytosol. Molecular Function: iron ion binding; heme binding; hemoglobin alpha binding; oxygen binding; oxygen transporter activity. Biological Process: protein heterooligomerization; oxygen transport; negative regulation of transcription from RNA polymerase II promoter; blood coagulation

0.1毫克

430美元