抗体

vi型胶原抗体

MBS535250

0.1毫克

340美元

多克隆

兔

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, 酶免疫法

抗体

vi型胶原抗体

[vi型胶原]

[Polyclonal Collagen Type VI; Anti-Collagen Type VI; CollagenVI; Human mRNA for collagen VI alpha 1 C terminal globular domain]

[胶原甲6(VI)链;胶原甲6(VI)链;胶原甲6(VI)链;胶原, 类型VI, 甲6]

[COL6A6;COL6A6]

CO6A6_HUMAN

多克隆

兔

Reacts with most mammalian Type VI collagens. Less than 1% cross reactivity with Type I, II, III, IV and V collagens

2263

牛/人类胶原VI

Collagen Type VI antibody was purified by affinity chromatography.

Supplied in 125mM Sodium Borate, pH 8.0, with 75mM Sodium Chloride, 5mM EDTA and 0.01% Sodium Azide

1.0 mg/ml by UV absorbance at 280 nm

Store at 4°C as an undiluted liquid. For extended storage, mix with an equal volume of glycerol and store at -20°C or below. Avoid freeze thaw cycles.

酶联免疫吸附测定(EIA), 免疫组化(免疫组化), 免疫沉淀(免疫沉淀), 免疫印迹(免疫印迹)

ELISA: 1:5,000-1:50,000. Western Blot: 1:1,000-1:10,000. IP: 1:100. IHC: 1:50-1:200

免疫组化免疫组化

Immunogen: Collagen type VI from human and bovine placenta. Biological Significance: Collagen is a group of naturally occurring proteins found, in nature, exclusively in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Collagen alpha-1(VI) chain is a protein that in humans is encoded by the COL6A1 gene. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. Bioactivity: Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues

Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Cancer; Purified Polyclonal Antibodies

亲和纯化兔多克隆vi型胶原抗体

Differential and restricted expression of novel collagen VI chains in mouse; Sudheer Kumar Gara, Paolo Grumati, Stefano Squarzoni, Patrizia Sabatelli, Anna Urciuolo, Paolo Bonaldo, Mats Paulsson, Raimund Wagener (Matrix Biology: Volume: 30 Issue: 4 Page: 248257 DOI: 10.1016/j.matbio.2011.03.006)

156616290

NP_001096078.1

NM_001102608.1

A6NMZ7

Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway (730306); Axon Guidance Pathway (105688); Collagen Biosynthesis And Modifying Enzymes Pathway (645289); Collagen Formation Pathway (645288); Developmental Biology Pathway (477129); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478)

COL6A6: Collagen VI acts as a cell-binding protein. Belongs to the type VI collagen family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: proteinaceous extracellular matrix; collagen; extracellular region. Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; cell adhesion

0.1毫克

340美元