抗体

CXCR2抗体

MBS535501

0.05毫克

540美元

多克隆

兔

nonconjugated

免疫组化, 免疫组化-石蜡切片

抗体

CXCR2抗体

CXCR2

Polyclonal CXCR2; Anti-CXCR2; il-8 receptor b; CXCR 2; interleukin 8 receptor beta; CXCR-2; cmkar2; interleukin-8 receptor b; cxcr2; Gro/mgsa receptor; il8r2; CXCR2; interleukin-8 receptor type b; il-8rb

interleukin 8 receptor B; C-X-C chemokine receptor type 2; C-X-C chemokine receptor type 2; chemokine (C-X-C motif) receptor 2; CDw128b; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2; CD_antigen: CD182

CXCR2

CXCR2;CXCR2;CD182;IL8R2;白细胞介素-8ra;白细胞介素-8rb;CMKAR2;CDw128b;白细胞介素-8rb;CXC-R2;CXCR-2;IL-8R B

CXCR2_HUMAN

多克隆

兔

To be determined by end-user

360

人类

CXCR2 antibody was purified by affinity chromatography.

Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.

1.0毫克/毫升

Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.

免疫组化(免疫组化)石蜡

免疫组化-P:5-10微克/毫升

Biological Significance: Interleukin 8 receptor, alpha is a chemokine receptor. IL8RA is its human gene. IL8RA has also been designated CD181 (cluster of differentiation 181), and CXCR1. The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system.

Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: CXCR2 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

细胞因子&生长因子

兔多克隆CXCR2抗体

186378

AAA36108.1

P25025

40,759 Da

Chemokine Receptors Bind Chemokines Pathway 106359!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Endocytosis Pathway 102279!!Endocytosis Pathway 102181!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 83102!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 515

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]

0.05毫克

540美元