产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
MCP1蛋白(小鼠)
目录 :
MBS538142
规格 :
0.01毫克
价格 :
310美元
更多信息或购买 :
产品信息
目录号 :
MBS538142
产品类型 :
重组蛋白
产品全称 :
MCP1蛋白(小鼠)
产品简称 :
MCP1
产品名称同义词 :
MCP-1 protein; MCP 1; MCP1; MCP 1 protein; Monocyte Chemotactic Protein-1 protein; MCP-1; CCL2 protein
其他名称 :
MCP1, partial; C-C motif chemokine 2; C-C motif chemokine 2; chemokine (C-C motif) ligand 2; HC11; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; MCAF; Monocyte chemotactic protein 1; MCP-1; Monocyte secretory protein JE; Small-inducible cytokine A2
产品基因名称 :
MCP1
其他基因名称 :
CCL2;CCL2;HC11;MCAF;MCP1;MCP-1;SCYA2;GDCF-2;SMC-CF;HSMCR30;MCP1;SCYA2;MCAF;MCP-1
UniProt数据库进入名 :
CCL2_HUMAN
宿主 :
小鼠
序列长度 :
25
序列 :
Region of MCP1 protein corresponding to amino acids QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN.
纯度 :
> 98% pure
形式 :
Supplied lyophilized with no additives. Reconstitute in sterile water to 0.1-1.0 mg/ml. Allow to set for at least 30 minutes.
储存稳定性 :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
检测过的应用 :
User optimized
其它信息1 :
Protein Type: Recombinant. Biological Significance: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Bioactivity: Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
其他信息2 :
Expression System: E Coli
产品种类 :
细胞因子&生长因子
产品描述 :
纯化重组小鼠MCP1蛋白
产品引用 :
Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons; Elisabeth Fr¸ylanda, Elena Didenko Pedersenb, Anne-Katrine Kvisselc, Runar Almaasd, Anne Pharob, Bj¸rn Steen Sk¥lhegge, Tom Eirik Mollnesb, Terje Rootwelt (Brain Research: Volume: 1113 Issue: 1 Page: 64-73 DOI: 10.1016/j.brainres.2006.07.051)
NCBI GI登录号 :
34559720
NCBI登录号 :
AAQ75526.1
UniProt数据库登录号 :
P13500
NCBI分子量 :
13.8 kDa
NCBI信号通路 :
ATF4 Activates Genes Pathway 530772!!Chagas Disease (American Trypanosomiasis) Pathway 147809!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Chemokine Receptors Bind Chemokines Pathway 106359!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!GPCR Ligand Binding Pathway 161020
NCBI总结 :
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013]
规格 :
0.01毫克
价格 :
310美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。