产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
IL17A蛋白(小鼠)
目录 :
MBS539491
规格 :
0.025毫克
价格 :
310美元
更多信息或购买 :
MyBioSource 产品网页
产品信息
目录号 :
MBS539491
产品类型 :
重组蛋白
产品全称 :
IL17A蛋白(小鼠)
产品简称 :
IL17A
产品名称同义词 :
ILA 17蛋白;白细胞介素17A蛋白;IL-17A蛋白;IL-17蛋白;CTLA-8蛋白;ILA-17蛋白;ILA-17;ILA 17;IL17A
其他名称 :
白细胞介素17A;白细胞介素17A;白细胞介素17A;白细胞介素17A;细胞毒性T淋巴细胞 抗原8;CTLA-8
产品基因名称 :
IL17A
其他基因名称 :
IL17A;IL17A;白细胞介素-17;CTLA8;IL-17;IL-17A;CTLA8;白细胞介素-17;IL-17;IL-17A;CTLA-8
UniProt数据库进入名 :
IL17_HUMAN
宿主 :
小鼠
序列长度 :
155
序列 :
Region of IL17A protein corresponding to amino acids MAAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA.
纯度 :
> 98% pure
形式 :
以冻干粉末状提供
储存稳定性 :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
检测过的应用 :
User optimized
其它信息1 :
Protein Type: Recombinant. Biological Significance: The originally described IL17 protein, now known as IL17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17A exhibits cross-species bioactivity between human and Mouse cells. Bioactivity: Measured by its ability to induce IL-6 production by NIH 3T3 cells. Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
其他信息2 :
Expression System: E Coli
产品种类 :
细胞因子&生长因子
产品描述 :
纯化重组小鼠IL17A蛋白
NCBI GI登录号 :
4504651
NCBI登录号 :
NP_002181.1
NCBI基因登录号 :
NM_002190.2
UniProt数据库登录号 :
Q16552
NCBI分子量 :
30 kDa
NCBI信号通路 :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!IL17 Signaling Pathway 920968!!IL23-mediated Signaling Events Pathway 138000!!IL27-mediated Signaling Events Pathway 137929!!Inflammatory Bowel Disease (IBD) Pathway 842771!!Inflammatory Bowel Disease (IBD) Pathway 842797!!Rheumatoid Arthritis Pathway 200309!!Rheumatoid Arthritis Pathway 200269!!TCR Signaling Pathway 198862
NCBI总结 :
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
规格 :
0.025毫克
价格 :
310美元
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。