产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
兔抗CD54(细胞间粘附分子 1)多克隆
目录 :
MBS551030
规格 :
0.1毫克
价格 :
280美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS551030
产品类型 :
抗体
产品全称 :
兔抗CD54(细胞间粘附分子 1)多克隆
产品简称 :
CD54(细胞间粘附分子 1)
产品名称同义词 :
Rabbit anti Human CD54 Polyclonal purified; icam1; icam-1; cd54; cd-54; polyclonal; PAb
其他名称 :
细胞间粘附分子1;细胞间粘附分子1;MALA-2;MyD10
产品基因名称 :
CD54
其他基因名称 :
Icam1; Icam-1; ICAM-1
UniProt数据库进入名 :
ICAM1_MOUSE
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
537
纯度 :
>95%. Purification: Serum IgG fraction was purified by Protein G affinity chromatography.
形式 :
冻干来自0.2um选择溶液在PBS pH值7.4
储存稳定性 :
The lyophilized antibody is stable for at least 1 year from date of receipt at -20 degree C. Upon reconstitution, this antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months without detectable loss of activity. Avoid repeated freeze/thaw cycles. Shelf Life: >12 months
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化)
应用笔记 :
ELISA: Use at a concentration range of 1-2 ug/ml. WB: Use at a concentration range of 2-10 ug/ml. IHC: A suitable range of concentrations of this antibody for IHC is 2-10 ug/ml.
其它信息1 :
Source Note: Polyclonal CD54 (ICAM1) antibody was produced from sera of rabbits immunized with synthetic protein containing CD54 antigenic determinants.
其他信息2 :
Reconstitution: A quick spin of the vial followed by reconstitution in 0.01M PBS pH 7.4 or other dilutents.
产品种类 :
多克隆
产品引用 :
prognostic and predictive impact of expression of the angiogenic markers cd105 and CD31 expression in patients with high risk breast cancer (hrbc). . Cancer Res., Dec 2009; 69: 2154. cd38/ CD31 , the ccl3 and ccl4 chemokines, and cd49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival . Cancer Res., May 2009; 69: 4001 - 4009. circulating monocytes expressing CD31 : implications for acute and chronic angiogenesis . Am. J. Pathol., May 2009; 174: 1972 - 1980. il-7 sustains CD31 expression in human naive cd4+ t cells and preferentially expands the CD31 + subset in a pi3k-dependent manner . Blood, Mar 2009; 113: 2999 - 3007. transcriptional profiling of CD31 + cells isolated from murine embryonic stem cells . Genes Cells, Feb 2009; 14: 243 - 260.
NCBI GI登录号 :
21389311
NCBI登录号 :
NP_034623.1
NCBI基因登录号 :
NM_010493.2
UniProt数据库登录号 :
P13597
NCBI分子量 :
58,844 Da
NCBI信号通路 :
Adaptive Immunity Signaling Pathway (366714); African Trypanosomiasis Pathway (194387); African Trypanosomiasis Pathway (194323); Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); IL-2 Signaling Pathway (198331); IL-5 Signaling Pathway (198281); Immune System Pathway (366713)
UniProt数据库总结 :
ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta. Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell adhesion. Cellular Component: extracellular space; focal adhesion; cell surface; membrane; integral to plasma membrane; integral to membrane; plasma membrane; immunological synapse; external side of plasma membrane; lipid raft. Molecular Function: integrin binding; protein complex binding. Biological Process: regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell adhesion; leukocyte adhesion; sensory perception of sound; positive regulation of actin filament polymerization; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; positive regulation of vasoconstriction; adhesion to host; cell adhesion mediated by integrin; cell adhesion; acute inflammatory response to antigenic stimulus
尺寸1 :
0.1毫克
价格1 :
280美元
尺寸2 :
0.2毫克
价格2 :
385
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。