[albumin; Serum albumin; serum albumin; OTTHUMP00000160370; OTTHUMP00000196832; OTTHUMP00000220435; OTTHUMP00000220436; OTTHUMP00000220438; OTTHUMP00000220439; growth-inhibiting protein 20; cell growth inhibiting protein 42; albumin]
Whole Serum. Physical State: Liquid
4 degree C for short term; -20 degree C or -70 degree C for long term.
By IEP analysis and gel diffusion, this product only reacts with albumin.
Preservative: 0.1% Sodium azide. Procedure: Goats were immunized with highly purified human serum albumin. Total protein value as measured by refractometer = 73 mg/ml.
Goats were immunized with highly purified normal human albumin. The resulting antiserum was passed over an antigen containing immunoabsorbant from which the anti-human albumin antibodies were immunoaffinity purified. Purification was followed by conjugation with horseradish peroxidase (HRP).
NCBI GI登录号 :
Bile Acid And Bile Salt Metabolism Pathway (106144); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Formation Of Platelet Plug Pathway (106029); HDL-mediated Lipid Transport Pathway (106158); Hemostasis Pathway (106028); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Of Lipids And Lipoproteins Pathway (160976); Platelet Activation Pathway (106034); Platelet Degranulation Pathway (106050)
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq]
albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Carrier; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; protein complex; extracellular region; basement membrane; nucleus. Molecular Function: antioxidant activity; toxin binding; protein binding; copper ion binding; enzyme binding; DNA binding; zinc ion binding; chaperone binding; drug binding; oxygen binding; fatty acid binding; pyridoxal phosphate binding. Biological Process: platelet activation; receptor-mediated endocytosis; sodium-independent organic anion transport; bile acid metabolic process; maintenance of mitochondrion localization; hemolysis by symbiont of host red blood cells; lipoprotein metabolic process; cellular response to starvation; response to mercury ion; bile acid and bile salt transport; response to organic substance; retinal homeostasis; platelet degranulation; transport; negative regulation of programmed cell death; blood coagulation; positive regulation of circadian sleep/wake cycle, non-REM sleep; transmembrane transport; response to nutrient; negative regulation of apoptosis. Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic
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