产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
人类阿尔法1抗糜蛋白酶酶联免疫吸附试剂盒
目录 :
MBS564032
规格 :
1 x96 Wells
价格 :
390美元
更多信息或购买 :
产品信息
目录号 :
MBS564032
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
人类阿尔法1抗糜蛋白酶酶联免疫吸附试剂盒
产品简称 :
阿尔法1抗糜蛋白酶
产品名称同义词 :
人类阿尔法1抗糜蛋白酶
其他名称 :
alpha-1-antichymotrypsin; Alpha-1-antichymotrypsin; alpha-1-antichymotrypsin; serpin A3; OTTHUMP00000028439; growth-inhibiting protein 24; growth-inhibiting protein 25; cell growth-inhibiting gene 24/25 protein; serine (or cysteine) proteinase inhibitor, clade A, member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; Cell growth-inhibiting gene 24/25 protein; Serpin A3
其他基因名称 :
SERPINA3;SERPINA3;ACT;AACT;GIG24;GIG25;MGC88254;AACT
UniProt数据库进入名 :
AACT_HUMAN
宿主 :
人类
储存稳定性 :
Store at 4 degree C.
其它信息1 :
Samples: Immunoperoxidase Assay for Determination of Alpha 1-Antichymotrypsin in Human Samples. Assay Type: Sandwich
其他信息2 :
Intended Uses: The Alpha 1-Antichymotrypsin (CYT) test kits are a highly sensitive two-site enzyme linked immunoassay (ELISA) for measuring alpha1-antichymotrypsin in biological fluid of humans.
产品种类 :
酶联免疫吸附试剂盒
产品描述 :
Principle of the Assay: The principle of the double antibody sandwich ELISA is represented in Figure 1. In this assay the Alpha 1-Antichymotrypsin present in samples reacts with the anti-Alpha 1-Antichymotrypsin antibodies which have been adsorbed to the surface of polystyrene microtitre wells. After the removal of unbound proteins by washing, anti-CYT antibodies conjugated with horseradish peroxidase (HRP), are added. These enzyme-labeled antibodies form complexes with the previously bound CYT. Following another washing step, the enzyme bound to the immunosorbent is assayed by the addition of a chromogenic substrate, 3,3',5,5'-tetramethylbenzidine (TMB). The quantity of bound enzyme varies directly with the concentration of CYT in the sample tested; thus, the absorbance, at 450 nm, is a measure of the concentration of CYT in the test sample. The quantity of CYT in the test sample can be interpolated from the standard curve constructed from the standards, and corrected for sample dilution.
NCBI GI登录号 :
50659080
NCBI登录号 :
NP_001076.2
NCBI基因登录号 :
NM_001085.4
UniProt数据库登录号 :
P01011
NCBI分子量 :
47,651 Da
NCBI信号通路 :
硒通路(198825)
NCBI总结 :
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq]
UniProt数据库总结 :
SERPINA3: Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. Belongs to the serpin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 14q32.1. Cellular Component: extracellular space; extracellular region; intracellular; nucleus. Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; DNA binding. Biological Process: regulation of lipid metabolic process; maintenance of gastrointestinal epithelium; acute-phase response; inflammatory response
尺寸1 :
1 x96 Wells
价格1 :
390美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。