抗体

肌动蛋白, 甲, 平滑肌

MBS609618

5毫升

410美元

单克隆

小鼠

未共轭

5F160

人类, 小鼠, 大鼠, 鸡, 牛

免疫印迹, 免疫组化, 免疫细胞化学

抗体

肌动蛋白, 甲, 平滑肌

肌动蛋白, 甲, 平滑肌

Anti -Actin, alpha, Smooth Muscle

actin, alpha 2, smooth muscle, aorta, isoform CRA_a; Actin, aortic smooth muscle; actin, aortic smooth muscle; alpha-cardiac actin; cell growth-inhibiting gene 46 protein; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein

大动脉平滑肌肌动蛋白alpha2;大动脉平滑肌肌动蛋白alpha2;AAT6;ACTSA;MYMY5;ACTSA;ACTVS

ACTA_HUMAN

单克隆

IgG2a

5F160

小鼠

Bovine, Chicken, Equine, Human, Mouse, Rat

Recognizes alpha-smooth-muscle isoform of actin (Mr 43,000). Reactivities on cultured stress fibers of smooth muscle-derived cells. Tumors specificallly detected

Affinity Purified. Purified by Protein A affinity chromatography.

以溶解在PBS液体方式提供, pH值7.4, 0.5% BSA, 0.09% 叠氮化钠

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)

Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry (frozen and paraffin-embedded tissue as well as cytological material). Dilution: Immunohistochemistry: Ready-to-use on frozen sections. Paraffin embedded sections require protease pretreatment prior to antibody application. Incubate 1 hour at RT; extended with paraffin. Optimal dilution to be determined by researcher.

Immunogen: Synthetic N-terminus decapeptide of alpha-smooth-muscle isoform of actin.

Antibodies; Abs to Actin Related Proteins

Represents an excellent marker for myogenic soft tissue tumors and smooth muscle differentiation, cultured stress fibers of smooth muscle-derived cells, and some smooth muscle subtype fibroblasts.

119570540

EAW50155.1

P62736

42,009 Da

Muscle Contraction Pathway (106261); Myometrial Relaxation And Contraction Pathways (198759); Smooth Muscle Contraction Pathway (161025); Striated Muscle Contraction Pathway (198903); Vascular Smooth Muscle Contraction Pathway (96530); Vascular Smooth Muscle Contraction Pathway (96866)

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

ACTA2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the actin family. Protein type: Contractile; Cytoskeletal; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 10q23.3. Cellular Component: extracellular space; protein complex; smooth muscle contractile fiber; cytoplasm; cytosol; actin cytoskeleton. Molecular Function: protein kinase binding; ATP binding. Biological Process: muscle contraction; regulation of blood pressure; response to virus; vascular smooth muscle contraction. Disease: Multisystemic Smooth Muscle Dysfunction Syndrome; Moyamoya Disease 5; Aortic Aneurysm, Familial Thoracic 6

5毫升

410美元