产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
Regenerating Protein 1 alpha (REG-1 alpha)
目录 :
MBS620035
规格 :
0.1毫克
价格 :
495美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS620035
产品类型 :
抗体
产品全称 :
Regenerating Protein 1 alpha (REG-1 alpha)
产品简称 :
Regenerating Protein 1 alpha
产品名称同义词 :
Anti -Regenerating Protein 1 alpha (REG-1 alpha)
其他名称 :
regenerating islet-derived protein 3-alpha; Regenerating islet-derived protein 3-alpha; regenerating islet-derived protein 3-alpha; REG-3-alpha; reg III-alpha; PAP homologous protein; human proislet peptide; pancreatitis-associated protein 1; proliferation-inducing protein 34; proliferation-inducing protein 42; hepatocarcinoma-intestine-pancreas; pancreatic beta cell growth factor; hepatointestinal pancreatic protein; regenerating islet-derived protein III-alpha; regenerating islet-derived 3 alpha; Hepatointestinal pancreatic protein; HIP/PAP; Human proislet peptide; Pancreatitis-associated protein 1; Regenerating islet-derived protein III-alpha
其他基因名称 :
REG3A;REG3A;髋;PAP;PAP1;REG3;INGAP;PAP-H;PBCGF;髋/PAP;REG-III;髋;PAP;PAP1;REG-3;髋/PAP
UniProt数据库进入名 :
REG3A_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类
特异性 :
Recognizes human Regenerating Protein 1 alpha.
纯度 :
亲和纯化。 经免疫亲和层析纯化
形式 :
Supplied as a lyophilized powder from PBS, pH 7.2. No preservative added. Reconstitute with 100ul sterile ddH2O.
储存稳定性 :
-20 degree C
检测过的应用 :
酶联免疫吸附测定(EL/EIA), 免疫印迹(免疫印迹), 免疫沉淀(免疫沉淀), 免疫细胞化学(免疫细胞化学)
应用笔记 :
适合用途包括酶联免疫吸附测定, 免疫印迹, 免疫沉淀和免疫组化
其它信息1 :
Immunogen: Recombinant corresponding to 156aa of human Regenerating Protein 1 alpha expressed in E. coli.
产品种类 :
Antibodies; Abs to Proteins
产品描述 :
Reg protein was shown to be stimulated during the regeneration of pancreatic islets. Since then, many Reg-related proteins have been identified in humans and other animals. In human, the four REG family genes, i.e., REG 1 alpha, REG 1 beta, REG-related sequence (RS) and HIP/PAP, have so far been isolated. These Reg-related proteins are classified into four subfamilies according to their aa sequences, but they share a similar structure and physiological function. Reg is a growth factor for pancreatic beta cells and suggests that the administration of Reg could be used as another therapeutic approach for diabetes mellitus. Human REG cDNA encodes a 166aa protein with a 22aa signal peptide. The aa sequence of human REG has 68% homology to that of rat Reg. Reg 1 was found to be expressed mainly in pancreatic beta and acinoductular cells as well as gastric fundic enterochromaffin-like (ECL) cells. Reg I production in ECL cells is stimulated by gastrin, as well as by the proinflammatory cytokine, cytokine-induced neutrophil chemoattractant (CINC)-2Beta. In patients with chronic hypergastrinemia, Reg production is stimulated with the increased proliferation of gastric mucosal cells. Patients with Helicobacter pylori infection also showed increased Reg production in the gastric mucosa, partly via increased plasma gastrin concentration and partly via increased proinflammatory cytokine production. The serum concentration of the reg-protein was significantly higher in patients with various pancreatic diseases than in normal controls, and was also significantly higher in patients with acute pancreatitis or chronic relapsing pancreatitis than in patients with chronic pancreatitis. Furthermore, the serum PSP/reg-protein concentration was also significantly increased in liver cirrhosis, choledocholit-hiasis and various cancers of the digestive system.
NCBI GI登录号 :
4505605
NCBI登录号 :
NP_002571.1
NCBI基因登录号 :
NM_002580.2
UniProt数据库登录号 :
Q06141
NCBI分子量 :
19,395 Da
NCBI总结 :
This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Dec 2010]
UniProt数据库总结 :
REG3A: Might be a stress protein involved in the control of bacterial proliferation. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 2p12. Cellular Component: extracellular space; cytoplasm. Molecular Function: carbohydrate binding. Biological Process: heterophilic cell adhesion; cell proliferation; multicellular organismal development; negative regulation of keratinocyte differentiation; acute-phase response
尺寸1 :
0.1毫克
价格1 :
495美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。