产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CTP Phosphocholine cytidylyltransferase (CCT alpha, CCTa)
目录 :
MBS620699
规格 :
0.1毫升
价格 :
465美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
产品信息
目录号 :
MBS620699
产品类型 :
抗体
产品全称 :
CTP Phosphocholine cytidylyltransferase (CCT alpha, CCTa)
产品简称 :
CTP Phosphocholine cytidylyltransferase
产品名称同义词 :
Anti -CTP Phosphocholine cytidylyltransferase (CCT alpha, CCTa)
其他名称 :
CTP:phosphocholine cytidylyltransferase; Choline-phosphate cytidylyltransferase A; choline-phosphate cytidylyltransferase A; CT A; CCT A; CCT-alpha; OTTHUMP00000208442; OTTHUMP00000208443; OTTHUMP00000208444; OTTHUMP00000208447; phosphorylcholine transferase A; CTP:phosphocholine cytidylyltransferase A; phosphate cytidylyltransferase 1, choline, alpha; CCT-alpha; CTP:phosphocholine cytidylyltransferase A; CCT A; CT A; Phosphorylcholine transferase A
其他基因名称 :
PCYT1A;PCYT1A;CT;CTA;CCTA;CTPCT;PCYT1;CTPCT;PCYT1
UniProt数据库进入名 :
PCY1A_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类
特异性 :
Recognizes human CTP Phosphocholine Cytidylytransferase at 42kD.
纯度 :
Affinity Purified. Purified by Protein A affinity chromatography.
形式 :
Supplied as a liquid in 10mM sodium HEPES pH 7.5, 150mM NaCl, 0.1mg/ml BSA and 50% glycerol.
储存稳定性 :
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
检测过的应用 :
免疫印迹(免疫印迹), 免疫沉淀(免疫沉淀)。 其他未被检测的应用
应用笔记 :
Suitable for use in Western Blot and Immunoprecipitation. Dilution: . Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1%. Tween-20 at 4 degree C with gentle shaking, overnight. Immunoprecipitation: 1:50. Optimal dilutions to be determined by the researcher.
其它信息1 :
Immunogen: Synthetic peptide corresponding to residues near the amino terminus of human CCT Alpha protein.
产品种类 :
Antibodies; Abs to Enzymes
产品描述 :
CTP:phosphocholine cytidylyltransferase (CCT) is a critical enzyme that regulates the CDP-choline pathway for the biosynthesis of phosphatidylcholine. Three distinct CCT isoforms are found in mammals, including CCTa, CCTB2, and CCTB3 (1,2). CCTa is the major isoform that is expressed in most tissues (3). CCTa is essential in the synthesis and secretion of surfactant by alveolar epithelial cells and is important in maintaining the phosphatidylcholine level that regulates lipoprotein as- sembly and secretion in hepatocytes (4,5). CCTa is a major component in membrane biogenesis during cytokine secretion by stimulated macrophages (6). Monoubiquitination of CCTa prevents it from entering the nucleus and leads to its degradation by lysosome (7).
NCBI GI登录号 :
575486
UniProt数据库登录号 :
P49585
NCBI分子量 :
41,731 Da
NCBI信号通路 :
Acetylcholine Synthesis Pathway (198820); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolic Pathways (132956)
NCBI总结 :
This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
UniProt数据库总结 :
PCYT1A: Controls phosphatidylcholine synthesis. Homodimer. By phosphorylation. Belongs to the cytidylyltransferase family. Protein type: Transferase; EC 2.7.7.15; Lipid Metabolism - glycerophospholipid. Chromosomal Location of Human Ortholog: 3q29. Cellular Component: endoplasmic reticulum membrane; glycogen granule; cytosol. Molecular Function: choline-phosphate cytidylyltransferase activity; protein homodimerization activity; lipid binding. Biological Process: CDP-choline pathway; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylcholine biosynthetic process. Disease: Spondylometaphyseal Dysplasia With Cone-rod Dystrophy
尺寸1 :
0.1毫升
价格1 :
465美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。