抗体

雌激素, 总数

MBS620830

1000试验

370美元

多克隆

兔

未共轭

酶联免疫吸附测定, 放射免疫分析法, 酶免疫法

抗体

雌激素, 总数

雌激素, 总数

Anti -Estrogen, Total

estrogen receptor beta; Estrogen receptor beta; estrogen receptor beta; estrogen receptor 2 beta; nuclear receptor subfamily 3 group A member 2; estrogen receptor 2 (ER beta); Nuclear receptor subfamily 3 group A member 2

Esr2;Esr2;Erb2;雌激素受体β;ER乙;雌激素受体β;Nr3a2;ER乙

ESR2_RAT

多克隆

IgG

兔

Recognizes total Estrogen: 100%.

血清。 血清

Supplied as a liquid. No preservatives added

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

酶联免疫吸附测定(EL/EIA), 放射免疫分析法(RIA)

Suitable for use in RIA and ELISA. Dilution: RIA: 33,000test/ml

Immunogen: Estriol (BSA)

Antibodies; Abs to Hormones, Steroids

3077649

CAA05631.1

Q62986

59,152 Da

Androgen Receptor Signaling Pathway (198529); Estrogen Signaling Pathway (799190); Estrogen Signaling Pathway (799197); Gene Expression Pathway (828948); Generic Transcription Pathway (828949); Nuclear Receptor Transcription Pathway (828951); Nuclear Receptors Pathway (198498); Ovarian Infertility Genes Pathway (198450); Prolactin Signaling Pathway (814205); Prolactin Signaling Pathway (814248)

binds estrogen and mediates transcriptional activation [RGD, Feb 2006]

ER-beta: a nuclear hormone receptor and transcription factor. Binds and activated by estrogen. Regulates gene expression and affects cellular proliferation and differentiation in target tissues. Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Eight alternatively-spliced isoforms have been described. Isoform beta-cx lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability. Protein type: Nuclear receptor; DNA-binding. Cellular Component: neuron projection; cell soma; mitochondrion; perinuclear region of cytoplasm; cytoplasm; plasma membrane; perikaryon; nucleus; cilium. Molecular Function: peroxisome proliferator activated receptor binding; ligand-dependent nuclear receptor activity; estrogen receptor activity; hormone binding; zinc ion binding; estrogen response element binding; drug binding; steroid binding; protein binding; enzyme binding; DNA binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription factor activity. Biological Process: prostate gland development; hypothalamus development; behavioral fear response; estrogen receptor signaling pathway; negative regulation of smooth muscle cell proliferation; positive regulation of apoptosis; induction of apoptosis by hormones; positive regulation of transcription, DNA-dependent; response to hormone stimulus; neuron migration; amygdala development; negative regulation of transcription from RNA polymerase II promoter; response to insecticide; uterus development; response to organic cyclic substance; response to estradiol stimulus; negative regulation of cell proliferation; learning and/or memory; ovarian follicle development; regulation of transcription, DNA-dependent; positive regulation of epidermal growth factor receptor signaling pathway; regulation of neuron apoptosis; cerebellum development; female gonad development; negative regulation of epithelial cell proliferation; response to nutrient levels; response to drug; steroid hormone receptor signaling pathway; transcription, DNA-dependent; male gonad development; vagina development; Sertoli cell proliferation; response to testosterone stimulus; Sertoli cell development; regulation of cell proliferation; response to genistein; response to ethanol; response to estrogen stimulus; positive regulation of transcription factor activity; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; response to activity; brain development; negative regulation of behavior; response to water deprivation

1000试验

370美元