Actin, Cardiac | MyBioSource MBS635219 产品信息

产品简要

公司名称 :

MyBioSource

产品类型 :

蛋白

产品名称 :

Actin, Cardiac

MBS635219

规格 :

0.1毫克

价格 :

535美元

更多信息或购买 :

MyBioSource 产品网页

产品信息

目录号 :

MBS635219

产品类型 :

蛋白

产品全称 :

Actin, Cardiac

产品简称 :

Actin, Cardiac

其他名称 :

actin, alpha cardiac muscle 1 proprotein; Actin, alpha cardiac muscle 1; actin, alpha cardiac muscle 1; actin, alpha, cardiac muscle 1; Alpha-cardiac actin

其他基因名称 :

ACTC1;ACTC1;ACTC;ASD5;CMD1R;CMH11;LVNC4;ACTC

UniProt数据库进入名 :

ACTC_HUMAN

宿主 :

牛心

纯度 :

>98% (SDS-PAGE)

形式 :

以冻干粉末状提供来自10mM三羟甲基氨基甲烷醋酸盐缓冲液, pH值8.0, 0.2mM氯化钙, 0.2mM三磷酸腺苷, 1mM DTT, 0.5% 十二烷基磺酸钠

浓度 :

~1mg/ml (after reconstitution)

储存稳定性 :

Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile H2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

检测过的应用 :

Gel Shift Assay (GS/EMSA)

应用笔记 :

Suitable for use as a Protein standard in 1D and 2D SDS gel electrophoresis, in Immunoassays and for Immunization.

其它信息1 :

Isoelectric Point: pI 5.4. Reconstitution: Reconstitute to <1mg/ml with sterile ddH2O.

产品种类 :

Molecular Biology; MB-Actin Related Proteins

NCBI GI登录号 :

4885049

NCBI登录号 :

NP_005150.1

NCBI基因登录号 :

NM_005159.4

UniProt数据库登录号 :

P68032

NCBI分子量 :

43kD

NCBI信号通路 :

Cardiac Progenitor Differentiation Pathway (712094); Cardiac Muscle Contraction Pathway (93344); Cardiac Muscle Contraction Pathway (93992); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Hypertrophic Cardiomyopathy (HCM) Pathway (114229); Hypertrophic Cardiomyopathy (HCM) Pathway (106591); Myometrial Relaxation And Contraction Pathways (198759); Striated Muscle Contraction Pathway (198903)

NCBI总结 :

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]

UniProt数据库总结 :

ACTC1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Protein type: Contractile; Cytoskeletal; Motility/polarity/chemotaxis; Cell development/differentiation; Myosin-binding. Chromosomal Location of Human Ortholog: 15q14. Cellular Component: I band; extracellular space; sarcomere; focal adhesion; membrane; cytoplasm; actin filament; cytosol. Molecular Function: myosin binding; ATPase activity; ATP binding. Biological Process: response to drug; apoptosis; metabolic process; muscle thin filament assembly; actin filament-based movement; actomyosin structure organization and biogenesis; cardiac myofibril assembly; muscle filament sliding; response to ethanol; heart contraction; cardiac muscle morphogensis; actin-myosin filament sliding; negative regulation of apoptosis; cardiac muscle contraction. Disease: Atrial Septal Defect 5; Cardiomyopathy, Familial Hypertrophic, 11; Cardiomyopathy, Dilated, 1r

尺寸1 :

0.1毫克

价格1 :

535美元

更多信息或购买 :

MyBioSource 产品网页

公司信息