产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
大鼠抗小鼠IL-17
目录 :
MBS670088
规格 :
0.5毫克
价格 :
320美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
nonconjugated
克隆名称 :
TC11-8H4
反应物种 :
人类, 小鼠
应用 :
酶联免疫吸附测定
更多信息或购买 :
MyBioSource 产品网页
产品信息
目录号 :
MBS670088
产品类型 :
抗体
产品全称 :
大鼠抗小鼠IL-17
产品简称 :
IL-17
产品名称同义词 :
Rat Anti-Mouse IL-17 - Purified, Unlabeled Antibody; Rat Anti-Mouse IL-17
其他名称 :
IL-17;白细胞介素17A;白细胞介素17A;CTLA-8;细胞毒性T淋巴细胞 抗原8;细胞毒性T淋巴细胞 蛋白8;白细胞介素17(细胞毒性T淋巴细胞 丝氨酸酯酶8);白细胞介素17A;细胞毒性T淋巴细胞 抗原8
其他基因名称 :
IL17A;IL17A;白细胞介素-17;CTLA8;IL-17;IL-17A;CTLA8;白细胞介素-17;IL-17;IL-17A;CTLA-8
UniProt数据库进入名 :
IL17_HUMAN
克隆性 :
单克隆
抗体亚型 :
大鼠IgG1k
克隆 :
TC11-8H4
宿主 :
大鼠
反应物种 :
小鼠
特异性 :
小鼠白细胞介素17(IL-17)
形式 :
纯化(UNLB)抗体
储存稳定性 :
The purified (UNLB) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg labeled antibody in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. Reagents are stable for the period shown on the label if stored as directed.
检测过的应用 :
酶联免疫吸附测定
应用笔记 :
Research Application(s): ELISA Detection: TC11-8H4 monoclonal antibody is useful as a detection antibody in a sandwich ELISA for quantifying mouse IL-17 protein levels. Biotinylated TC11-8H4 antibody should be paired with purified TC11-18H10 antibody as the capture antibody, with purified recombinant mouse IL- 17 as the standard. Since applications vary, each investigator should determine the optimal concentration appropriate for individual applications.
其它信息1 :
Immunogen: E. coli-expressed recombinant mouse IL-17
其他信息2 :
Characterization: To ensure acceptable performance, each batch of product is tested in a sandwich ELISA to conform to characteristics of a standard reference reagent.
NCBI GI登录号 :
1155223
NCBI登录号 :
AAC50341.1
UniProt数据库登录号 :
Q16552
NCBI分子量 :
17,504 Da
NCBI信号通路 :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!IL23-mediated Signaling Events Pathway 138000!!IL27-mediated Signaling Events Pathway 137929!!Inflammatory Bowel Disease (IBD) Pathway 842771!!Inflammatory Bowel Disease (IBD) Pathway 842797!!Rheumatoid Arthritis Pathway 200309!!Rheumatoid Arthritis Pathway 200269!!TCR Signaling Pathway 198862
NCBI总结 :
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
Function: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Subunit structure: Homodimer. Ref.8. Subcellular location: Secreted. Tissue specificity: Restricted to activated memory T-cells. Post-translational modification: Found both in glycosylated and nonglycosylated forms. Sequence similarities: Belongs to the IL-17 family.
规格 :
0.5毫克
价格 :
320美元
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。