产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
小鼠抗人类CTGF
目录 :
MBS690096
规格 :
0.1毫克
价格 :
490美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
[(6B13)]
反应物种 :
人类
应用 :
酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS690096
产品类型 :
抗体
产品全称 :
小鼠抗人类CTGF
产品简称 :
[CTGF]
产品名称同义词 :
[抗人类CTGF(#6B13)]
其他名称 :
[connective tissue growth factor; Connective tissue growth factor; connective tissue growth factor; IBP-8; IGFBP-8; CCN family member 2; IGF-binding protein 8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8; connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8]
产品基因名称 :
[CTGF]
其他基因名称 :
[CTGF;CTGF;CCN2;NOV2;HCS24;IGFBP8;CCN2;HCS24;IGFBP8;IBP-8;IGF结合蛋白8;IGFBP-8]
UniProt数据库进入名 :
CTGF_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1
克隆 :
[(6B13)]
宿主 :
小鼠
反应物种 :
人类
序列长度 :
349
特异性 :
This antibody recognizes human CTGF with Elisa and immunohistochemistry.
纯度 :
蛋白质G色谱
形式 :
冻干
储存稳定性 :
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity. Ships on cold packs
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫组化(免疫组化)
应用笔记 :
1. Immunohistochemistry (Paraffin): Yes (1:50-200) 2. Elisa: Yes
image1头 :
免疫组化
其它信息1 :
Synonyms (TARGET): CTGF; CCN2; NOV2; HCS24; IGFBP8. Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human Connective Tissue Growth Factor (CTGF). The IgG1 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography. Antigen: Human recombinant CTGF
其他信息2 :
Reconstitution buffer: PBS (Sterile). Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
产品描述 :
CTGF belongs to the CCN (CYR61/CTGF/NOV) family of secreted proteins that share a common multimodular organization. Each protein contains an IGF-binding protein domain, a von Willebrand factor type C domain, a thrombospondin type I domain, and a cysteine knot domain. The multimodular CTGF has the ability to bind multiple ligands and has numerous effects on development, differentation, and disease. The C-terminal cysteine knot motif contains the heparin and low density lipoprotein receptor (LDLR) binding sites that contribute to the adhesive and mitogenic properties of CTGF.
NCBI GI登录号 :
4503123
NCBI登录号 :
NP_001892.1
NCBI基因登录号 :
NM_001901.2
UniProt数据库登录号 :
P29279
NCBI信号通路 :
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); TGF-beta Receptor Signaling Pathway (138024)
NCBI总结 :
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]
UniProt数据库总结 :
Function: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Ref.14 Ref.15. Subunit structure: Monomer. Subcellular location: Secreted extracellular space extracellular matrix . By similarity. Secreted . By similarity. Tissue specificity: Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. Ref.13. Sequence similarities: Belongs to the CCN family.Contains 1 CTCK (C-terminal cystine knot-like) domain.Contains 1 IGFBP N-terminal domain.Contains 1 TSP type-1 domain.Contains 1 VWFC domain.
尺寸1 :
0.1毫克
价格1 :
490美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。