产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
仓鼠抗小鼠CD28
目录 :
MBS690499
规格 :
0.1毫克
价格 :
490美元
克隆性 :
单克隆
宿主 :
golden hamster
共轭标签 :
未共轭
克隆名称 :
[(MAB0711)]
反应物种 :
小鼠
应用 :
免疫组化, 流式细胞仪, 流式细胞仪
更多信息或购买 :
图像
图像 1 :
Formalin fixed and paraffin embedded mouse thymus tissue section was subjected to IHC staining of CD28 using MBS690499 (Left panel: Red Pulp, Right panel: White Pulp)
图像 2 :
Formalin fixed and paraffin embedded mouse tumor section was subjected to IHC staining of CD28 using MBS690499 (Left panel: x20; Right panel: x40).
产品信息
目录号 :
MBS690499
产品类型 :
抗体
产品全称 :
仓鼠抗小鼠CD28
产品简称 :
[CD28]
产品名称同义词 :
[抗小鼠CD28]
其他名称 :
[T细胞表面的糖蛋白CD28;T细胞表面的糖蛋白CD28;T细胞表面的糖蛋白CD28;CD28抗原]
产品基因名称 :
[CD28]
其他基因名称 :
[Cd28;Cd28]
UniProt数据库进入名 :
CD28_MOUSE
克隆性 :
单克隆
抗体亚型 :
IgG
克隆 :
[(MAB0711)]
宿主 :
Syrian Hamster
反应物种 :
小鼠
序列长度 :
218
特异性 :
This antibody was selected for its ability to detect mouse CD28
纯度 :
蛋白质A/G亲和色谱
形式 :
冻干
储存稳定性 :
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least for six months without detectable loss of activity. Shipping: 4°C or RT
检测过的应用 :
免疫组化(免疫组化), 流式细胞仪(FC/流式细胞仪)
应用笔记 :
Immunohistochemistry (Paraffin): 1:50-300 . Flow Cytometery: 1:100-1000
image1头 :
免疫组化
image2头 :
免疫组化
其它信息1 :
Preparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a Golden Syrian Hamster immunized with recombinant mouse CD28 protein). IgG fraction of the culture supernatant was purified by Protein G affinity chromatography. Antigen: Recombinant mouse CD28
其他信息2 :
Reconstitution: Reconstitute the antibody with 400 ul sterile PBS and the final concentration is 500 ug/ml. Reconstitution Buffer: PBS (sterile)
产品描述 :
CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Mouse CD28 is expressed constitutively on virtually 100% of mouse Tcells and on developing thymocytes.
NCBI GI登录号 :
161484597
NCBI登录号 :
NP_031668.3
NCBI基因登录号 :
NM_007642.4
UniProt数据库登录号 :
P31041
NCBI分子量 :
25,243 Da
NCBI信号通路 :
Allograft Rejection Pathway (83316); Allograft Rejection Pathway (535); Autoimmune Thyroid Disease Pathway (83314); Autoimmune Thyroid Disease Pathway (533); Cell Adhesion Molecules (CAMs) Pathway (83266); Cell Adhesion Molecules (CAMs) Pathway (480); Graft-versus-host Disease Pathway (83317); Graft-versus-host Disease Pathway (536); Inflammatory Response Pathway (198280); Intestinal Immune Network For IgA Production Pathway (128761)
UniProt数据库总结 :
Function: Possibly involved in T-cell activation. Subunit structure: Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70 . By similarity. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.
尺寸1 :
0.1毫克
价格1 :
490美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。