产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
人类IGF-BP2
目录 :
MBS692085
规格 :
0.005毫克
价格 :
200美元
更多信息或购买 :
产品信息
目录号 :
MBS692085
产品类型 :
重组蛋白
产品全称 :
人类IGF-BP2
产品简称 :
[IGF-BP2]
产品名称同义词 :
[重组人类IGF-碱基对]
其他名称 :
[胰岛素样生长因子结合蛋白2;胰岛素样生长因子结合蛋白2;胰岛素样生长因子结合蛋白2;IBP-2;IGFBP-2;IGF结合蛋白2;胰岛素样生长因子结合蛋白2, 36kDa]
产品基因名称 :
[IGF-BP2]
其他基因名称 :
[IGFBP2;IGFBP2;IBP2;IGF-BP53;BP2;IBP2;IBP-2;IGF结合蛋白2;IGFBP-2]
UniProt数据库进入名 :
IBP2_HUMAN
宿主 :
昆虫细胞
反应物种 :
人类
序列长度 :
289
序列 :
EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREP GCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM G EGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGG GSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KL RPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKH GL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLF YNEQQEA RGVHTQRMQ
纯度 :
> 98% by SDS-PAGE & HPLC analyses
形式 :
冻干
储存稳定性 :
The lyophilized protein is stable at room temperature for 1 month and at 4 degree C for 6 months. Reconstituted working aliquots are stable for 1 week at 2 degree C to 8 degree C and for 3 months at -20 degree C to -80 degree C. Avoid repeated freeze and thaw cycles.
其它信息1 :
Endotoxin Level: < 0.1 ng/ug of protein (1<1EU/ug).
其他信息2 :
Biological Activity: Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells. Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2-8 degree C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20 degree to -80 degree C.
产品种类 :
细胞因子&生长因子
产品描述 :
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells. Recombinant human IGF-BP2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.
NCBI GI登录号 :
55925576
NCBI登录号 :
NP_000588.2
NCBI基因登录号 :
NM_000597.2
UniProt数据库登录号 :
P18065
NCBI分子量 :
31.5 kDa
NCBI信号通路 :
Metabolism Of Proteins Pathway (106230); Myometrial Relaxation And Contraction Pathways (198759); Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway (105908)
UniProt数据库总结 :
Function: Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Ref.11. Subunit structure: Binds IGF2 more than IGF1. Subcellular location: Secreted. Domain: The C-terminus is required for IGF-binding and growth inhibition. Ref.11. Post-translational modification: O-glycosylated. Ref.10. Sequence similarities: Contains 1 IGFBP N-terminal domain.Contains 1 thyroglobulin type-1 domain.
尺寸1 :
0.005毫克
价格1 :
200美元
尺寸2 :
0.02毫克
价格2 :
340
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。