抗体

兔抗人类白细胞介素-8受体, 乙多克隆抗体

MBS711346

0.05毫升

375美元

多克隆

兔

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 酶免疫法

抗体

兔抗人类白细胞介素-8受体, 乙多克隆抗体

白细胞介素-8受体, 乙

白细胞介素-8受体;乙;白细胞介素-8rb;CD182;CDw128b;CMKAR2;CXCR2;IL8R2;白细胞介素-8ra

Interleukin 8 receptor, beta; C-X-C chemokine receptor type 2; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; IL-8 receptor type 2; interleukin 8 receptor B; chemokine (CXC) receptor 2; interleukin 8 receptor, beta; interleukin 8 receptor type 2; interleukin-8 receptor type B; CXCR2 gene for IL8 receptor type B; high affinity interleukin-8 receptor B; chemokine (C-X-C motif) receptor 2; CDw128b; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2; CD_antigen: CD182

CXCR2;CXCR2;CD182;IL8R2;白细胞介素-8ra;白细胞介素-8rb;CMKAR2;CDw128b;白细胞介素-8rb;CXC-R2;CXCR-2;IL-8R B

CXCR2_HUMAN

多克隆

IgG

兔

人类

360

抗原亲和纯化

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫荧光(IF)

Immunogen: Human IL8RB

Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

37572263

AAH37961.2

40,759 Da

Chemokine Receptors Bind Chemokines Pathway 106359!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Endocytosis Pathway 102279!!Endocytosis Pathway 102181!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 83102!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 515

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]

0.05毫升

375美元