产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
Rabbit anti-human glutathione S-transferase mu 5 polyclonal Antibody
目录 :
MBS712299
规格 :
0.05毫升
价格 :
375美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法
更多信息或购买 :
文章摘录数: 1
参考文献
Kratzer I, Strazielle N, Saudrais E, Mönkkönen K, Malleval C, Blondel S, et al. Glutathione Conjugation at the Blood-CSF Barrier Efficiently Prevents Exposure of the Developing Brain Fluid Environment to Blood-Borne Reactive Electrophilic Substances. J Neurosci. 2018;38:3466-3479 pubmed 出版商
产品信息
目录号 :
MBS712299
产品类型 :
抗体
产品全称 :
Rabbit anti-human glutathione S-transferase mu 5 polyclonal Antibody
产品简称 :
glutathione S-transferase mu 5
产品名称同义词 :
glutathione S-transferase mu 5; GSTM5; GSTM5-5; GTM5
其他名称 :
glutathione S-transferase Mu 5; Glutathione S-transferase Mu 5; glutathione S-transferase Mu 5; GST class-mu 5; glutathione S-transferase M5; glutathione S-aryltransferase M5; glutathione S-alkyltransferase M5; glutathione S-aralkyltransferase M5; S-(hydroxyalkyl)glutathione lyase M5; glutathione S-transferase mu 5; GST class-mu 5; GSTM5-5
其他基因名称 :
GSTM5;GSTM5;GTM5;GSTM5-5
UniProt数据库进入名 :
GSTM5_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
218
纯度 :
抗原亲和纯化
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)
其它信息1 :
Immunogen: Human GSTM5
其他信息2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
NCBI GI登录号 :
23065563
NCBI登录号 :
NP_000842.2
NCBI基因登录号 :
NM_000851.3
NCBI分子量 :
25,675 Da
NCBI信号通路 :
Biological Oxidations Pathway (105698); Chemical Carcinogenesis Pathway (673221); Chemical Carcinogenesis Pathway (673237); Drug Metabolism - Cytochrome P450 Pathway (83032); Drug Metabolism - Cytochrome P450 Pathway (427); Glutathione Conjugation Pathway (105727); Glutathione Metabolism Pathway (82973); Glutathione Metabolism Pathway (343); Metabolism Pathway (477135); Metabolism Of Xenobiotics By Cytochrome P450 Pathway (83031)
NCBI总结 :
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
GSTM5: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Mu family. Protein type: EC 2.5.1.18; Other Amino Acids Metabolism - glutathione; Transferase; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450. Chromosomal Location of Human Ortholog: 1p13.3. Cellular Component: cytosol. Molecular Function: glutathione transferase activity. Biological Process: glutathione metabolic process; xenobiotic metabolic process
尺寸1 :
0.05毫升
价格1 :
375美元
尺寸2 :
0.15毫升
价格2 :
715
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。