抗体

Rabbit anti-human phosphoserine aminotransferase 1 polyclonal Antibody

MBS712314

0.05毫升

375美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法

抗体

Rabbit anti-human phosphoserine aminotransferase 1 polyclonal Antibody

phosphoserine aminotransferase 1

phosphoserine aminotransferase 1; PSAT1; EPIP; MGC1460; PSA; PSAT

Phosphoserine aminotransferase 1; Phosphoserine aminotransferase; phosphoserine aminotransferase; endometrial progesterone-induced protein; phosphohydroxythreonine aminotransferase; phosphoserine aminotransferase 1; Phosphohydroxythreonine aminotransferase; PSAT

PSAT1;PSAT1;PSA;EPIP;NLS2;PSAT;PSATD;PSA;PSAT

SERC_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

370

抗原亲和纯化

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)

Immunogen: Human PSAT1

Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

17390289

AAH18129.1

35,189 Da

Amino Acid Synthesis And Interconversion (transamination) Pathway (106173); Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Glycine, Serine And Threonine Metabolism Pathway (82949); Glycine, Serine And Threonine Metabolism Pathway (313); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169)

This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, and 8. [provided by RefSeq, Jul 2013]

PSAT1: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. Defects in PSAT1 are the cause of phosphoserine aminotransferase deficiency (PSATD). PSATD is characterized biochemically by low plasma and cerebrospinal fluid concentrations of serine and glycine and clinically by intractable seizures, acquired microcephaly, hypertonia, and psychomotor retardation. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.6.1.52; Amino Acid Metabolism - glycine, serine and threonine; Cofactor and Vitamin Metabolism - vitamin B6; Transferase. Chromosomal Location of Human Ortholog: 9q21.2. Cellular Component: cytoplasm; cytosol. Molecular Function: phosphoserine transaminase activity; pyridoxal phosphate binding. Biological Process: L-serine biosynthetic process; pyridoxine biosynthetic process; amino acid biosynthetic process. Disease: Phosphoserine Aminotransferase Deficiency; Neu-laxova Syndrome 2

0.05毫升

375美元

0.15毫升

715