产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
兔抗人类谷胱甘肽S转移甲1多克隆抗体
目录 :
MBS712341
规格 :
0.05毫升
价格 :
375美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法
更多信息或购买 :
产品信息
目录号 :
MBS712341
产品类型 :
抗体
产品全称 :
兔抗人类谷胱甘肽S转移甲1多克隆抗体
产品简称 :
谷胱甘肽S转移甲1
产品名称同义词 :
谷胱甘肽S转移甲1;GSTA1;GST2;GSTA1-1;GTH1;MGC131939
其他名称 :
Glutathione S-transferase alpha 1; Glutathione S-transferase A1; glutathione S-transferase A1; GST-epsilon; GST HA subunit 1; GST, class alpha, 1; GST class-alpha member 1; glutathione S-transferase 2; glutathione S-aryltransferase A1; glutathione S-alkyltransferase A1; S-(hydroxyalkyl)glutathione lyase A1; glutathione S-transferase Ha subunit 1; glutathione S-transferase alpha 1; GST HA subunit 1; GST class-alpha member 1; GST-epsilon; GSTA1-1; GTH1Cleaved into the following chain:Glutathione S-transferase A1, N-terminally processed
其他基因名称 :
GSTA1;GSTA1;GST2;GTH1;GSTA1-1
UniProt数据库进入名 :
GSTA1_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
222
纯度 :
抗原亲和纯化
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)
其它信息1 :
Immunogen: Human GSTA1
其他信息2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
NCBI GI登录号 :
83406048
NCBI登录号 :
AAI10892.1
NCBI分子量 :
25,631 Da
NCBI信号通路 :
4-hydroxy-2-nonenal Detoxification Pathway (703096); 4-hydroxy-2-nonenal Detoxification Pathway (703144); AhR Pathway (755436); Biological Oxidations Pathway (105698); Chemical Carcinogenesis Pathway (673221); Chemical Carcinogenesis Pathway (673237); Drug Metabolism - Cytochrome P450 Pathway (83032); Drug Metabolism - Cytochrome P450 Pathway (427); Glutathione Conjugation Pathway (105727); Glutathione Metabolism Pathway (82973)
NCBI总结 :
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
GSTA1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Alpha family. Protein type: Other Amino Acids Metabolism - glutathione; EC 2.5.1.18; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Transferase. Chromosomal Location of Human Ortholog: 6p12.1. Cellular Component: cytosol. Molecular Function: glutathione transferase activity. Biological Process: glutathione metabolic process; epithelial cell differentiation; metabolic process; xenobiotic metabolic process
尺寸1 :
0.05毫升
价格1 :
375美元
尺寸2 :
0.15毫升
价格2 :
715
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。