抗体

兔抗人类踝蛋白1多克隆抗体

MBS713788

0.05毫升

375美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 酶免疫法

抗体

兔抗人类踝蛋白1多克隆抗体

踝蛋白1

踝蛋白1;TLN1;ILWEQ;KIAA1027;TLN

踝蛋白1;踝蛋白1;踝蛋白1;踝蛋白1

TLN1;TLN1;TLN;ILWEQ;KIAA1027;TLN

TLN1_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

2541

抗原亲和纯化

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF)

Immunogen: Human TLN1

Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

27552808

AAH42923.1

269,767 Da

Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); EGF Receptor (ErbB1) Signaling Pathway (137970); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); GRB2:SOS Provides Linkage To MAPK Signaling For Integrins Pathway (106055); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Hemostasis Pathway (106028)

This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]

Talin-1: a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. Protein type: Cytoskeletal; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 9p13. Cellular Component: ruffle; focal adhesion; cell surface; cytoplasm; plasma membrane; extracellular region; microtubule organizing center; intercellular junction; cytosol. Molecular Function: integrin binding; actin filament binding; protein binding; LIM domain binding; structural constituent of cytoskeleton; insulin receptor binding; vinculin binding. Biological Process: axon guidance; intercellular junction assembly; platelet activation; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; platelet degranulation; muscle contraction; cytoskeletal anchoring; unfolded protein response; cell-substrate junction assembly; cortical actin cytoskeleton organization and biogenesis; blood coagulation; cell motility

0.05毫升

375美元

0.15毫升

715