产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
兔抗人类血管细胞粘附分子多克隆抗体
目录 :
MBS714395
规格 :
0.05毫升
价格 :
375美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
酶联免疫吸附测定, 免疫组化, 酶免疫法
更多信息或购买 :
MyBioSource 产品网页
产品信息
目录号 :
MBS714395
产品类型 :
抗体
产品全称 :
兔抗人类血管细胞粘附分子多克隆抗体
产品简称 :
血管细胞粘附分子
产品名称同义词 :
血管细胞粘附分子;血管细胞粘附分子1;CD106;DKFZp779G2333;INCAM-100;MGC99561
其他名称 :
vascular cell adhesion molecule 1; Vascular cell adhesion protein 1; vascular cell adhesion protein 1; CD106 antigen; vascular cell adhesion molecule 1; INCAM-100; CD_antigen: CD106
其他基因名称 :
血管细胞粘附分子1;血管细胞粘附分子1;CD106;INCAM-100;L1细胞粘附分子;V-CAM 1;VCAM-1
UniProt数据库进入名 :
VCAM1_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
647
纯度 :
抗原亲和纯化
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫组化(免疫组化)
其它信息1 :
Immunogen: Human VCAM-1
其他信息2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
NCBI GI登录号 :
179886
NCBI登录号 :
AAA51917.1
NCBI分子量 :
74,346 Da
NCBI信号通路 :
Adaptive Immune System Pathway (366160); African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cellular Roles Of Anthrax Toxin Pathway (138076); Cytokine Signaling In Immune System Pathway (366171); Extracellular Matrix Organization Pathway (576262); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889)
NCBI总结 :
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
UniProt数据库总结 :
VCAM1: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 1p32-p31. Cellular Component: Golgi apparatus; extracellular space; microvillus; cell surface; endoplasmic reticulum; early endosome; integral to membrane; apical part of cell; plasma membrane; podosome; sarcolemma; external side of plasma membrane; filopodium. Molecular Function: amine oxidase activity; integrin binding; cell adhesion molecule binding. Biological Process: response to nicotine; regulation of immune response; chronic inflammatory response; extracellular matrix organization and biogenesis; viral reproduction; cytokine and chemokine mediated signaling pathway; heart development; cell-matrix adhesion; response to lipopolysaccharide; heterophilic cell adhesion; leukocyte adhesion; response to ethanol; response to zinc ion; B cell differentiation; membrane to membrane docking; response to hypoxia; positive regulation of T cell proliferation; amine metabolic process; response to ionizing radiation; cell adhesion; leukocyte tethering or rolling; response to nutrient; acute inflammatory response; aging
尺寸1 :
0.05毫升
价格1 :
375美元
尺寸2 :
0.15毫升
价格2 :
715
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。