抗体

Rabbit anti-human v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) polyclonal Antibody

MBS716069

0.05毫升

375美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

Rabbit anti-human v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) polyclonal Antibody

v-erb-a erythroblastic leukemia viral oncogene homolog 4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); ERBB4; HER4; MGC138404; p180erbB4

V-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); Receptor tyrosine-protein kinase erbB-4; receptor tyrosine-protein kinase erbB-4; proto-oncogene-like protein c-ErbB-4; tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4; Proto-oncogene-like protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; p180erbB4Cleaved into the following chain:ERBB4 intracellular domain; 4ICD; E4ICDAlternative name(s):s80HER4

ERBB4;ERBB4;HER4;ALS19;p180erbB4;HER4;4ICD;E4ICD

ERBB4_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

1292

抗原亲和纯化

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

Immunogen: Human ERBB4

Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

219521515

AAI43742.1

143,968 Da

Adaptive Immune System Pathway 366160!!Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Disease Pathway 530764!!Downregulation Of ERBB4 Signaling Pathway 530745!!Downstream Signal Transduction Pathway 106385!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 576250

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

0.05毫升

375美元