抗体

Rabbit anti-human prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) polyclonal Antibody

MBS716487

0.05毫升

375美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 酶免疫法

抗体

Rabbit anti-human prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) polyclonal Antibody

前列腺素内过氧化物合酶1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); PTGS1; COX1; COX3; PCOX1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS

prostaglandin-endoperoxide synthase 1; Prostaglandin G/H synthase 1; prostaglandin G/H synthase 1; PGH synthase 1; cyclooxygenase-1; prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1

PTGS1; PTGS1; COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1; COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1

PGH1_HUMAN

多克隆

IgG

兔

Human, Mouse, Rat; Other species are not tested. Please decide the specificity by homology.

599

抗原亲和纯化

液体

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫组化(免疫组化)

ELISA: Use at an assay dependent dilution. WB: 1:200-1:2000 . IHC: 1:20-1:200 (Recommender dilutions) . Positive WB detected in : Mouse lung tissue, mouse kidney tissue . Positive IHC detected in : Human stomach tissue

Conjugate: Non-conjugated . Immunogen: Human PTGS1

Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.

May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.

17017287

AAL33601.1

72,010 Da

Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (685553); Arachidonic Acid Metabolism Pathway (366); Biological Oxidations Pathway (105698); C20 Prostanoid Biosynthesis Pathway (908107); COX Reactions Pathway (105711); Eicosanoid Synthesis Pathway (198888); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976)

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

COX-1: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Homodimer. Belongs to the prostaglandin G/H synthase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid Metabolism - arachidonic acid; EC 1.14.99.1; Oxidoreductase. Chromosomal Location of Human Ortholog: 9q32-q33.3. Cellular Component: endoplasmic reticulum membrane; photoreceptor outer segment; intracellular membrane-bound organelle; cytoplasm; nucleus. Molecular Function: prostaglandin-endoperoxide synthase activity; peroxidase activity; dioxygenase activity; metal ion binding; heme binding. Biological Process: xenobiotic metabolic process; regulation of blood pressure; cyclooxygenase pathway; arachidonic acid metabolic process; lipid metabolic process; response to oxidative stress; prostaglandin biosynthetic process; inflammatory response; regulation of cell proliferation

0.05毫升

375美元

0.15毫升

715