抗体

兔抗人类加热休克27kDa蛋白1多克隆抗体

MBS716588

0.05毫升

375美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 酶免疫法

抗体

兔抗人类加热休克27kDa蛋白1多克隆抗体

加热休克27kDa蛋白1

加热休克27kDa蛋白1;HSPB1;CMT2F;DKFZp586P1322;HMN2B;HS.76067;HSP27;HSP28;Hsp25;SRP27

heat shock 27kDa protein 1; Heat shock protein beta-1; heat shock protein beta-1; HSP 27; 28 kDa heat shock protein; heat shock 27 kDa protein; heat shock 27kD protein 1; stress-responsive protein 27; estrogen-regulated 24 kDa protein; epididymis secretory protein Li 102; heat shock 27kDa protein 1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27

HSPB1;HSPB1;CMT2F;HMN2B;HSP27;HSP28;Hsp25;SRP27;HS.76067;HEL-S-102;HSP27;HSP28;HspB1;HSP 27;SRP27

HSPB1_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

205

抗原亲和纯化

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 免疫荧光(IF)

Immunogen: Human HSPB1

Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

119592209

EAW71803.1

22,783 Da

AUF1 (hnRNP D0) Destabilizes MRNA Pathway (187212); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); FAS Pathway And Stress Induction Of HSP Regulation (198894); Gene Expression Pathway (105937); IL-3 Signaling Pathway (198881); IL-6 Signaling Pathway (198864); MAPK Signaling Pathway (198779)

The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008]

HSP27: a small heat shock protein that is regulated both transcriptionally and posttranslationally. Modulates actin polymerization and reorganization. Its expression level increases several-fold in response to stress and is phosphorylated by MAPKAP kinase 2. Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock. Protein type: Motility/polarity/chemotaxis; Chaperone; Heat shock protein. Chromosomal Location of Human Ortholog: 7q11.23. Cellular Component: proteasome complex; extracellular space; focal adhesion; cytoskeleton; cytoplasm; plasma membrane; spindle; cytosol; nucleus; Z disc. Molecular Function: identical protein binding; protein kinase C inhibitor activity; protein binding; ubiquitin binding; protein kinase C binding; protein kinase binding. Biological Process: positive regulation of interleukin-1 beta production; retinal homeostasis; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of angiogenesis; response to virus; positive regulation of blood vessel endothelial cell migration; negative regulation of protein kinase activity; gene expression; regulation of I-kappaB kinase/NF-kappaB cascade; cell motility; vascular endothelial growth factor receptor signaling pathway; response to unfolded protein; negative regulation of apoptosis; regulation of translational initiation. Disease: Neuronopathy, Distal Hereditary Motor, Type Iib; Charcot-marie-tooth Disease, Axonal, Type 2f

0.05毫升

375美元

0.15毫升

715