抗体

Rabbit anti-human v-crk sarcoma virus CT10 oncogene homolog (avian) polyclonal Antibody

MBS716944

0.05毫升

375美元

多克隆

兔

未共轭

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

Rabbit anti-human v-crk sarcoma virus CT10 oncogene homolog (avian) polyclonal Antibody

v-crk sarcoma virus CT10 oncogene homolog

v-crk sarcoma virus CT10 oncogene homolog (avian); CRK; CRKII

V-crk sarcoma virus CT10 oncogene homolog (avian); Adapter molecule crk; adapter molecule crk; proto-oncogene c-Crk; v-crk avian sarcoma virus CT10 oncogene homolog; Proto-oncogene c-Crk; p38

CRK;CRK;p38;CRKII

CRK_HUMAN

多克隆

IgG

兔

人类, 小鼠, 大鼠

304

抗原亲和纯化

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

Immunogen: Human CRK

Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.

45708482

AAH01718.1

22,906 Da

ARMS-mediated Activation Pathway 106466!!Angiopoietin Receptor Tie2-mediated Signaling Pathway 137917!!B Cell Receptor Signaling Pathway 198909!!Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!CXCR4-mediated Signaling Events Pathway 137910!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Chronic Myeloid Leukemia Pathway 83116!!Chronic Myeloid Leukemia Pathway 528

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]

0.05毫升

375美元