产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
Recombinant Human Complement receptor type 1 (CR1), partial
目录 :
MBS717740
规格 :
0.5毫克(大肠杆菌)
价格 :
945美元
更多信息或购买 :
产品信息
目录号 :
MBS717740
产品类型 :
重组蛋白
产品全称 :
Recombinant Human Complement receptor type 1 (CR1), partial
产品简称 :
Complement receptor type 1 (CR1), partial
产品名称同义词 :
1型补体受体;C3b/C4b受体;CD_antigen=;CD35
其他名称 :
complement receptor type 1 isoform F; Complement receptor type 1; complement receptor type 1; CD35 antigen; C3b/C4b receptor; C3-binding protein; Knops blood group antigen; complement component (3b/4b) receptor 1 (Knops blood group); C3b/C4b receptor; CD_antigen: CD35
产品基因名称 :
CR1
产品基因名称同义词 :
CR1;C3BR
其他基因名称 :
CR1;CR1;KN;C3BR;C4BR;CD35;C3BR
UniProt数据库进入名 :
CR1_HUMAN
宿主 :
E Coli or Yeast or Baculovirus or Mammalian Cell
序列位置 :
901-1095
纯度 :
>90%
形式 :
Liquid containing glycerol; lyophilization may be available upon request.
储存稳定性 :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
其它信息1 :
Species: Homo sapiens (Human)
产品描述 :
CR1;C3BR
NCBI GI登录号 :
86793036
NCBI登录号 :
NP_000564.2
NCBI基因登录号 :
NM_000573.3
UniProt数据库登录号 :
P17927
NCBI分子量 :
223,663 Da
NCBI信号通路 :
Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Leishmaniasis Pathway (144181); Leishmaniasis Pathway (144028); Malaria Pathway (152665); Malaria Pathway (152657); Tuberculosis Pathway (213780)
NCBI总结 :
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
CR1: Mediates cellular binding of particles and immune complexes that have activated complement. Belongs to the receptors of complement activation (RCA) family. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q32. Cellular Component: cell surface; integral to plasma membrane; plasma membrane. Molecular Function: complement component C4b binding; complement component C3b receptor activity; complement component C4b receptor activity; complement component C3b binding. Biological Process: negative regulation of complement activation, alternative pathway; complement receptor mediated signaling pathway; negative regulation of complement activation, classical pathway; regulation of complement activation; innate immune response; complement activation, classical pathway. Disease: Knops Blood Group System; Malaria, Susceptibility To
尺寸1 :
0.5毫克(大肠杆菌)
价格1 :
945美元
尺寸2 :
0.05毫克(杆状病毒)
价格2 :
945
size3 :
0.5毫克(酵母)
价格3 :
1165
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1165
size5 :
1毫克(大肠杆菌)
price5 :
1390
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。