ELISA/assay

大鼠CD147/EMMPRIN酶联免疫吸附试剂盒

MBS722266

48-Strip-Wells

470美元

酶联免疫吸附试剂盒

大鼠CD147/EMMPRIN酶联免疫吸附试剂盒

CD147/EMMPRIN

CD147; Basigin; basigin; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagenase stimulatory factor; basigin (Ok blood group); 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD_antigen: CD147

CD147

BSG;BSG;M6;OK;5F7;TCSF;CD147;EMMPRIN;UNQ6505/PRO21383;EMMPRIN;TCSF

BASI_HUMAN

大鼠

Store all reagents at 2-8 degree C.

Assay Type: Competitive

Highest Standards: 2500pg/mL. Concentration of Standards: Concentration of Standards: 0,100,250,500,1000,2500pg/mL

免疫学

31076333

BAC76828.1

22,764 Da

Basigin Interactions Pathway (106065); Cell Surface Interactions At The Vascular Wall Pathway (106062); Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262); Hemostasis Pathway (106028); Integrin Cell Surface Interactions Pathway (106110); Matrix Metalloproteinases Pathway (198900); Metabolism Pathway (477135); Pyruvate Metabolism Pathway (106205); Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway (106327)

The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

BSG: Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor. Forms homooligomers in a cis-dependent manner on the plasma membrane. Forms a complex with MMP1 at the tumor cell surface. Interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. Interacts with ATP1B2, MAG and L1CAM. Interacts with AJAP1. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Immunoglobulin superfamily. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: Golgi membrane; focal adhesion; mitochondrion; membrane; integral to plasma membrane; melanosome; plasma membrane; sarcolemma; acrosomal membrane; lipid raft. Molecular Function: mannose binding; protein binding. Biological Process: response to mercury ion; cellular metabolic process; response to peptide hormone stimulus; extracellular matrix disassembly; extracellular matrix organization and biogenesis; cell surface receptor linked signal transduction; response to cAMP; decidualization; pyruvate metabolic process; blood coagulation; leukocyte migration; embryo implantation; odontogenesis of dentine-containing teeth. Disease: Blood Group--ok

48-Strip-Wells

470美元

96-Strip-Wells

675