产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
人类前列腺素内过氧化物合酶1酶联免疫吸附试剂盒
目录 :
MBS733514
规格 :
48-Strip-Wells-(Comp
价格 :
470美元
更多信息或购买 :
产品信息
目录号 :
MBS733514
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
人类前列腺素内过氧化物合酶1酶联免疫吸附试剂盒
产品简称 :
前列腺素内过氧化物合酶1
其他名称 :
prostaglandin-endoperoxide synthase 1; Prostaglandin G/H synthase 1; prostaglandin G/H synthase 1; PGH synthase 1; cyclooxygenase-1; prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
产品基因名称 :
PTGS1
其他基因名称 :
PTGS1; PTGS1; COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1; COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1
UniProt数据库进入名 :
PGH1_HUMAN
反应物种 :
人类
储存稳定性 :
Store all reagents at 2-8 degree C.
其它信息1 :
Assay Type: Competitive or Sandwich. Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Sensitivity: 1.0 pg/mL.
其他信息2 :
Intended Uses: This PTGS1 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Human PTGS1. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
产品描述 :
Principle of the Assay: PTGS1 ELISA kit applies the quantitative sandwich enzyme immunoassay technique. The microtiter plate has been pre-coated with a monoclonal antibody specific for PTGS1. Standards or samples are then added to the microtiter plate wells and PTGS1 if present, will bind to the antibody pre-coated wells. In order to quantitatively determine the amount of PTGS1 present in the sample, a standardized preparation of horseradish peroxidase (HRP) -conjugated polyclonal antibody, specific for PTGS1 are added to each well to "sandwich" the PTGS1 immobilized on the plate. The microtiter plate undergoes incubation, and then the wells are thoroughly washed to remove all unbound components. Next, substrate solutions are added to each well. The enzyme (HRP) and substrate are allowed to react over a short incubation period. Only those wells that contain PTGS1 and enzyme-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The PTGS1 concentration in each sample is interpolated from this standard curve.
NCBI GI登录号 :
17017287
NCBI登录号 :
AAL33601.1
NCBI分子量 :
72,010 Da
NCBI信号通路 :
Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (685553); Arachidonic Acid Metabolism Pathway (366); Biological Oxidations Pathway (105698); C20 Prostanoid Biosynthesis Pathway (908107); COX Reactions Pathway (105711); Eicosanoid Synthesis Pathway (198888); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976)
NCBI总结 :
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
UniProt数据库总结 :
COX-1: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Homodimer. Belongs to the prostaglandin G/H synthase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.14.99.1; Lipid Metabolism - arachidonic acid; Oxidoreductase. Chromosomal Location of Human Ortholog: 9q32-q33.3. Cellular Component: endoplasmic reticulum membrane; photoreceptor outer segment; intracellular membrane-bound organelle; cytoplasm; nucleus. Molecular Function: prostaglandin-endoperoxide synthase activity; peroxidase activity; dioxygenase activity; metal ion binding; heme binding. Biological Process: regulation of blood pressure; xenobiotic metabolic process; cyclooxygenase pathway; arachidonic acid metabolic process; response to oxidative stress; lipid metabolic process; prostaglandin biosynthetic process; inflammatory response; regulation of cell proliferation
尺寸1 :
48-Strip-Wells-(Competitive)
价格1 :
470美元
尺寸2 :
48-Strip-Wells-(Sandwich)
价格2 :
470
size3 :
96-Strip-Wells-(Competitive)
价格3 :
675
size4 :
96-Strip-Wells-(Sandwich)
price4 :
675
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。