产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
兔蛋白酶激活受体1酶联免疫吸附试剂盒
目录 :
MBS746436
规格 :
48-Strip-Wells
价格 :
470美元
更多信息或购买 :
产品信息
目录号 :
MBS746436
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
兔蛋白酶激活受体1酶联免疫吸附试剂盒
产品简称 :
蛋白酶激活受体1
其他名称 :
蛋白酶激活受体;蛋白酶激活受体;蛋白酶激活受体;蛋白酶激活受体1;凝血因子II(凝血酶)受体;凝血因子II受体;凝血酶受体
产品基因名称 :
PAR1
其他基因名称 :
F2R;F2R;TR;HTR;CF2R;PAR1;PAR-1;CF2R;PAR1;TR;PAR-1
UniProt数据库进入名 :
PAR1_HUMAN
反应物种 :
储存稳定性 :
Store all reagents at 2-8 degree C.
其它信息1 :
Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Sensitivity: 0.1 ng/mL.
其他信息2 :
Intended Uses: This PAR-1 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Rabbit PAR-1. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
产品种类 :
信号转导
NCBI GI登录号 :
166362740
NCBI登录号 :
NP_001983.2
NCBI基因登录号 :
NM_001992.3
NCBI分子量 :
47,441 Da
NCBI信号通路 :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Endocytosis Pathway (102279); Endocytosis Pathway (102181); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548)
NCBI总结 :
Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
PAR1: a G-protein coupled high-affinity receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelet activation and in vascular development. Protein type: Cell development/differentiation; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1. Chromosomal Location of Human Ortholog: 5q13. Cellular Component: Golgi apparatus; postsynaptic membrane; integral to plasma membrane; early endosome; plasma membrane; extracellular region; caveola; neuromuscular junction. Molecular Function: G-protein coupled receptor activity; protein binding; G-protein beta-subunit binding; G-protein alpha-subunit binding; receptor binding; thrombin receptor activity. Biological Process: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of blood coagulation; activation of MAPKK activity; negative regulation of glomerular filtration; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; positive regulation of caspase activity; positive regulation of JAK-STAT cascade; response to lipopolysaccharide; negative regulation of cell proliferation; elevation of cytosolic calcium ion concentration; connective tissue replacement during inflammatory response; positive regulation of MAPKKK cascade; platelet dense granule organization and biogenesis; regulation of interleukin-1 beta production; positive regulation of cell proliferation; protein kinase C activation; response to wounding; negative regulation of neuron apoptosis; positive regulation of smooth muscle contraction; inflammatory response; establishment of synaptic specificity at neuromuscular junction; STAT protein nuclear translocation; caspase activation; platelet activation; anatomical structure morphogenesis; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of Rho protein signal transduction; positive regulation of phosphoinositide 3-kinase cascade; G-protein coupled receptor protein signaling pathway; tyrosine phosphorylation of STAT protein; homeostasis of number of cells within a tissue; release of sequestered calcium ion into cytosol; regulation of blood coagulation; positive regulation of vasoconstriction; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of release of sequestered calcium ion into cytosol; regulation of sensory perception of pain; positive regulation of calcium ion transport; blood coagulation; positive regulation of cell migration
尺寸1 :
48-Strip-Wells
价格1 :
470美元
尺寸2 :
96-Strip-Wells
价格2 :
675
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。