磷酸化(409/410)-TDP43兔多克隆 | MyBioSource MBS7602634 产品信息

产品简要

公司名称 :

MyBioSource

产品类型 :

抗体

产品名称 :

磷酸化(409/410)-TDP43兔多克隆

MBS7602634

规格 :

0.1毫克

价格 :

290美元

克隆性 :

多克隆

宿主 :

兔

共轭标签 :

未共轭

应用 :

免疫印迹, 酶联免疫吸附测定, 酶免疫法

更多信息或购买 :

MyBioSource 产品网页

图像

图像 1 :

human placenta tissue were subjected to SDS PAGE followed by western blot with MBS7602634 (phospho(409/410)-TDP43 antibody) at dilution of 1:1000

产品信息

目录号 :

MBS7602634

产品类型 :

抗体

产品全称 :

磷酸化(409/410)-TDP43兔多克隆

产品简称 :

[磷酸化(409/410)-TDP43]

产品名称同义词 :

[磷酸化TDP43, 磷酸化(409/410)-TDP43, TARDBP, TDP43]

产品基因名称 :

[TDP43]

克隆性 :

多克隆

抗体亚型 :

IgG

宿主 :

兔

反应物种 :

Human, Mouse; other species are not tested.

特异性 :

Please decide the specificity by homology.

纯度 :

>=95% as determined by SDS-PAGE. Immunogen Affinity Purified

形式 :

Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

储存稳定性 :

-20°C for 24 months (Avoid repeated freeze / thaw cycles.)

检测过的应用 :

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

应用笔记 :

WB: 1:500-1:2000

image1头 :

免疫印迹

其它信息1 :

Immunogen: TAR DNA binding protein. Calculated MW: 48 kDa

产品描述 :

TDP-43 is a 414 amino acid (aa) nuclear DNA and RNA-binding protein which regulates transcription and splicing. TDP-43 is aberrantly expressed in most forms of amylotrophic lateral sclerosis and frontotemporal lobar degeneration. In these cases it is absent from the nucleus and accumulates, along with a truncated 25kDa form, in ubiquitin-containing inclusion bodies. Inpathological tissues, TDP-43 is highly phosphorylated and Ser409/410 is the main phosphorylation site. Among the TDP-43 protein fragments, the 25kDa fragment is also highly phosphorylated and widely believed to be pathogenic. This antibody is a rabbit polyclonal antibody recognizing TDP-43 only when phosphorylated at 409/410. This antibody detects phosphorylated forms of TDP-43 as well as the cleavage product of 25 kDa.

尺寸1 :

0.1毫克

价格1 :

290美元

更多信息或购买 :

MyBioSource 产品网页

公司信息