产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
CD27兔多克隆
目录 :
MBS767685
规格 :
0.1毫克
价格 :
265美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 流式细胞仪, 流式细胞仪, 酶免疫法
更多信息或购买 :
图像
图像 1 :
1X10^6 Raji cells were stained with 0.2ug CD27 antibody (MBS767685, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.
图像 2 :
Jurkat cells were subjected to SDS PAGE followed by western blot with MBS767685 (CD27 antibody) at dilution of 1:600
产品信息
目录号 :
MBS767685
产品类型 :
抗体
产品全称 :
CD27兔多克隆
产品简称 :
[CD27]
产品名称同义词 :
[CD27, CD27 antigen, CD27 molecule, CD27L receptor, S152, T cell activation antigen CD27, T14, TNFRSF7, Tp55]
其他名称 :
[CD27 antigen; CD27 antigen; CD27 antigen; CD27 molecule; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD_antigen: CD27]
产品基因名称 :
[CD27]
其他基因名称 :
[CD27;CD27;T14;S152;Tp55;TNFRSF7;S152。 LPFS2;TNFRSF7]
UniProt数据库进入名 :
CD27_HUMAN
克隆性 :
多克隆
抗体亚型 :
IgG
宿主 :
兔
反应物种 :
人类
序列长度 :
260
特异性 :
Other species are not tested. Please decide the specificity by homology
纯度 :
Purification: Immunogen affinity purified. Purity: > or =95% as determined by SDS-PAGE
形式 :
液体
储存稳定性 :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹), 流式细胞仪(FC/流式细胞仪)
应用笔记 :
WB: 1:500-1:1000
image1头 :
流式细胞仪
image2头 :
十二烷基磺酸钠-PAGE
其它信息1 :
Immunogen: CD27 molecule
NCBI GI登录号 :
4507587
NCBI登录号 :
NP_001233.1
NCBI基因登录号 :
NM_001242.4
UniProt数据库登录号 :
P26842
NCBI分子量 :
50 kDa
NCBI信号通路 :
Cytokine Signaling In Immune System Pathway (1269310); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Immune System Pathway (1269170); TNFR2 Non-canonical NF-kB Pathway (1269329); TNFs Bind Their Physiological Receptors Pathway (1269332)
NCBI总结 :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
CD27: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. Protein type: Receptor, cytokine; Apoptosis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: external side of plasma membrane; extracellular region; integral to plasma membrane; neuron projection; nucleus; plasma membrane. Molecular Function: caspase inhibitor activity; protein binding; transmembrane receptor activity; tumor necrosis factor receptor activity. Biological Process: brain development; cell surface receptor linked signal transduction; immune response; immunoglobulin mediated immune response; induction of apoptosis via death domain receptors; inflammatory response; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of B cell differentiation; positive regulation of JNK cascade; positive regulation of MAPKKK cascade; regulation of cell proliferation; release of cytoplasmic sequestered NF-kappaB; response to ethanol; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway. Disease: Lymphoproliferative Syndrome 2
尺寸1 :
0.1毫克
价格1 :
265美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。