产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
GFAP小鼠单克隆
目录 :
MBS769660
规格 :
0.1毫克
价格 :
290美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS769660 图像 1
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using MBS769660 ( GFAP Antibody) at dilution of 1:5000. Heat mediated antigen retrieved with Citric acid buffer, pH6.0.
图像 2 :
MyBioSource MBS769660 图像 2
U-251 cells were subjected to SDS PAGE followed by western blot with MBS769660 (GFAP antibody) at dilution of 1:10000.
产品信息
目录号 :
MBS769660
产品类型 :
抗体
产品全称 :
GFAP小鼠单克隆
产品简称 :
[GFAP]
产品名称同义词 :
[FLJ45472, GFAP]
其他名称 :
[胶质纤维酸性蛋白;胶质纤维酸性蛋白;胶质纤维酸性蛋白;胶质纤维酸性蛋白]
产品基因名称 :
[GFAP]
其他基因名称 :
[GFAP;GFAP;ALXDRD;GFAP]
UniProt数据库进入名 :
GFAP_HUMAN
克隆性 :
单克隆
抗体亚型 :
IgG1
宿主 :
小鼠
反应物种 :
Human, Mouse , Rat; other species are not tested.
序列长度 :
432
特异性 :
Please decide the specificity by homology
纯度 :
>=95% as determined by SDS-PAGE. Protein A+G purification
形式 :
Liquid. PBS with 0.02% sodium azide and 50% glycerol pH 7.3
储存稳定性 :
-20°C for 24 months (Avoid repeated freeze / thaw cycles.)
检测过的应用 :
酶联免疫吸附测定, 免疫印迹, 免疫组化
应用笔记 :
免疫印迹:1:5000-1:50000。 免疫组化:1:500-1:10000。 IF : 1:50-1:500
image1头 :
免疫组化(免疫组化)
image2头 :
十二烷基磺酸钠-PAGE
其它信息1 :
Immunogen: Glial fibrillary acidic protein
其他信息2 :
Calculated MW: 50 kDa
产品描述 :
GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
NCBI GI登录号 :
251802
NCBI登录号 :
AAB22581.1
NCBI信号通路 :
Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Neural Crest Differentiation Pathway (672460); Nuclear Signaling By ERBB4 Pathway (1269499); Signal Transduction Pathway (1269379); Signaling By ERBB4 Pathway (1269496); Spinal Cord Injury Pathway (739007)
NCBI总结 :
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
UniProt数据库总结 :
GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: cytoplasm; cytosol; intermediate filament; intermediate filament cytoskeleton; lysosome; membrane; myelin sheath. Molecular Function: glycoprotein binding; integrin binding; kinase binding; protein binding; structural constituent of cytoskeleton. Biological Process: astrocyte development; Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; intermediate filament organization; neurite regeneration; regulation of neurotransmitter uptake; regulation of protein complex assembly; response to wounding. Disease: Alexander Disease
尺寸1 :
0.1毫克
价格1 :
290美元
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。