产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗β葡萄糖苷酶2抗体
目录 :
MBS820370
规格 :
0.03毫升
价格 :
155美元
克隆性 :
多克隆
宿主 :
unidentified
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS820370 图像 1
Western blot analysis of Beta-glucosidase 2 expression in A431 (A), HeLa (B), A549 (C) whole cell lysates.
图像 2 :
MyBioSource MBS820370 图像 2
Immunofluorescent analysis of Beta-glucosidase 2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
产品信息
目录号 :
MBS820370
产品类型 :
抗体
产品全称 :
抗β葡萄糖苷酶2抗体
产品简称 :
[β葡萄糖苷酶2]
产品名称同义词 :
[G19P1; Glucosidase 2 subunit beta; 80K-H protein; Glucosidase II subunit beta; Protein kinase C substrate 60.1 kDa protein heavy chain; PKCSH]
其他名称 :
[glucosidase 2 subunit beta isoform 2; Glucosidase 2 subunit beta; glucosidase 2 subunit beta; hepatocystin; AGE-binding receptor 2; glucosidase II subunit beta; protein kinase C substrate, 80 Kda protein; protein kinase C substrate 60.1 kDa protein heavy chain; protein kinase C substrate 80K-H; 80K-H protein; Glucosidase II subunit beta; Protein kinase C substrate 60.1 kDa protein heavy chain; PKCSH]
产品基因名称 :
[PRKCSH]
其他基因名称 :
[PRKCSH;PRKCSH;PCLD;PLD1;G19P1;PKCSH;AGE-R2;G19P1;PKCSH]
UniProt数据库进入名 :
GLU2B_HUMAN
克隆性 :
多克隆
宿主 :
未知
反应物种 :
人类
序列长度 :
525
特异性 :
Recognizes endogenous levels of Beta-glucosidase 2 protein.
纯度 :
The antibody was purified by immunogen affinity chromatography.
形式 :
液体0.42% 钾磷酸盐, 0.87% 氯化钠, pH值7.3, 30% 甘油, 和0.01% 叠氮化钠
储存稳定性 :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
检测过的应用 :
Western Blot (WB), Immunofluorescence (IF), Immunocytochemsitry (ICC)
应用笔记 :
免疫印迹(1/500 - 1/1000);IF/免疫细胞化学(1/100 - 1/500)
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫荧光(IF)
其他信息2 :
Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Beta-glucosidase 2. The exact sequence is proprietary.
产品描述 :
兔多克隆抗体β葡萄糖苷酶2
NCBI GI登录号 :
48255891
NCBI登录号 :
NP_001001329.1
NCBI基因登录号 :
NM_001001329.2
UniProt数据库登录号 :
P14314
NCBI分子量 :
59,178 Da
NCBI信号通路 :
Advanced Glycosylation Endproduct Receptor Signaling Pathway (187092); Asparagine N-linked Glycosylation Pathway (161013); Calnexin/calreticulin Cycle Pathway (187218); Immune System Pathway (106386); Innate Immune System Pathway (106387); Metabolism Of Proteins Pathway (106230); N-glycan Trimming In The ER And Calnexin/Calreticulin Cycle Pathway (187217); Post-translational Protein Modification Pathway (161012); Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190)
NCBI总结 :
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
UniProt数据库总结 :
PRKCSH: Regulatory subunit of glucosidase II. Defects in PRKCSH are a cause of polycystic liver disease (PCLD). PCLD is an autosomal dominant disorder and is characterized by the presence of multiple liver cysts of biliary epithelial origin. PCLD is a distinct clinical and genetic entity that can occur independently from autosomal dominant polycystic kidney disease (ADPKD), which in a considerable but uncertain proportion of cases is associated with hepatic cysts. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: endoplasmic reticulum lumen; endoplasmic reticulum; intracellular. Molecular Function: protein kinase C binding; phosphoprotein binding; calcium ion binding. Biological Process: cellular protein metabolic process; protein folding; innate immune response; protein amino acid N-linked glycosylation via asparagine; N-glycan processing; post-translational protein modification. Disease: Polycystic Liver Disease
尺寸1 :
0.03毫升
价格1 :
155美元
尺寸2 :
0.1毫升
价格2 :
220
size3 :
0.2毫升
价格3 :
295
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。