产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗LIF抗体
目录 :
MBS820385
规格 :
0.03毫升
价格 :
155美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹
更多信息或购买 :
图像
图像 1 :
MyBioSource MBS820385 图像 1
Western blot analysis of LIF expression in Jurkat (A), NIH3T3 (B), PC12 (C) whole cell lysates.
产品信息
目录号 :
MBS820385
产品类型 :
抗体
产品全称 :
抗LIF抗体
产品简称 :
[LIF]
产品名称同义词 :
[HILDA; Leukemia inhibitory factor; LIF; Differentiation-stimulating factor; D factor; Melanoma-derived LPL inhibitor; MLPLI; Emfilermin]
其他名称 :
[leukemia inhibitory factor isoform 2; Leukemia inhibitory factor; leukemia inhibitory factor; D factor; human interleukin in DA cells; melanoma-derived LPL inhibitor; differentiation-inducing factor; hepatocyte-stimulating factor III; cholinergic differentiation factor; differentiation-stimulating factor; differentiation inhibitory activity; leukemia inhibitory factor; Differentiation-stimulating factor; D factor; Melanoma-derived LPL inhibitor; MLPLI; INN: Emfilermin]
产品基因名称 :
[LIF]
其他基因名称 :
[LIF; LIF; CDF; DIA; HILDA; MLPLI; HILDA; LIF; D factor; MLPLI]
UniProt数据库进入名 :
LIF_HUMAN
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠, 大鼠, 牛, 猪, 羊
序列长度 :
88
特异性 :
Recognizes endogenous levels of LIF protein.
纯度 :
The antibody was purified by immunogen affinity chromatography.
形式 :
液体0.42% 钾磷酸盐, 0.87% 氯化钠, pH值7.3, 30% 甘油, 和0.01% 叠氮化钠
储存稳定性 :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
免疫印迹(1/500 - 1/1000)
image1头 :
免疫印迹(免疫印迹)
其他信息2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LIF. The exact sequence is proprietary.
产品描述 :
兔多克隆抗体LIF
NCBI GI登录号 :
380418324
NCBI登录号 :
NP_001244064.1
NCBI基因登录号 :
NM_001257135.1
UniProt数据库登录号 :
P15018
NCBI信号通路 :
Adipogenesis Pathway (198832); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Direct P53 Effectors Pathway (137939); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); MicroRNAs In Cardiomyocyte Hypertrophy Pathway (198784); Signaling Pathways Regulating Pluripotency Of Stem Cells (1026136); Signaling Pathways Regulating Pluripotency Of Stem Cells (1033502); TGF Beta Signaling Pathway (198810)
NCBI总结 :
The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
UniProt数据库总结 :
LIF: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. Belongs to the LIF/OSM family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 22q12.2. Cellular Component: extracellular space; cytoplasm. Molecular Function: growth factor activity; leukemia inhibitory factor receptor binding; cytokine activity; receptor binding. Biological Process: transcription from RNA polymerase II promoter; multicellular organismal development; leukemia inhibitory factor signaling pathway; negative regulation of hormone secretion; tyrosine phosphorylation of Stat3 protein; decidualization; positive regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of cell proliferation; positive regulation of MAPKKK cascade; positive regulation of cell proliferation; negative regulation of meiosis; positive regulation of macrophage differentiation; muscle morphogenesis; positive regulation of astrocyte differentiation; positive regulation of peptidyl-serine phosphorylation of STAT protein; stem cell maintenance; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of tyrosine phosphorylation of Stat1 protein; neuron development; blood vessel remodeling; positive regulation of transcription from RNA polymerase II promoter; immune response; alveolus development; embryo implantation
尺寸1 :
0.03毫升
价格1 :
155美元
尺寸2 :
0.1毫升
价格2 :
220
size3 :
0.2毫升
价格3 :
295
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。