产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗水闸蛋白4抗体
目录 :
MBS820456
规格 :
0.03毫升
价格 :
155美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
产品信息
目录号 :
MBS820456
产品类型 :
抗体
产品全称 :
抗水闸蛋白4抗体
产品简称 :
水闸蛋白4
产品名称同义词 :
CPER; CPETR1; WBSCR8; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein
其他名称 :
claudin-4; Claudin-4; claudin-4; CPE-receptor; Clostridium perfringens enterotoxin receptor 1; Williams-Beuren syndrome chromosomal region 8 protein; claudin 4; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein
产品基因名称 :
CLDN4
其他基因名称 :
CLDN4;CLDN4;CPER;CPE-R;CPETR;CPETR1;WBSCR8;hCPE-R;CPER;CPETR1;WBSCR8;CPE-R;CPE受体
UniProt数据库进入名 :
CLD4_HUMAN
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 猪, 兔, 羊
序列长度 :
209
特异性 :
Recognizes endogenous levels of Claudin 4 protein.
纯度 :
The antibody was purified by immunogen affinity chromatography.
形式 :
液体0.42% 钾磷酸盐, 0.87% 氯化钠, pH值7.3, 30% 甘油, 和0.01% 叠氮化钠
储存稳定性 :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化)
应用笔记 :
WB (1/500 - 1/1000), IH (1/100 - 1/200). Western blot analysis of Claudin 4 expression in DLD (A), SW480 (B), LS1034 (C), MIA (D), PaCa2 (E) whole cell lysates. Immunohistochemical analysis of Claudin 4 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
其他信息2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Claudin 4. The exact sequence is proprietary.
产品描述 :
兔多克隆抗体水闸蛋白4
NCBI GI登录号 :
4502877
NCBI登录号 :
NP_001296.1
NCBI基因登录号 :
NM_001305.4
UniProt数据库登录号 :
O14493
NCBI分子量 :
22,077 Da
NCBI信号通路 :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-cell Junction Organization Pathway (119532); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494); Tight Junction Pathway (83071)
NCBI总结 :
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
UniProt数据库总结 :
Claudin-4: Plays a major role in tight junction-specific obliteration of the intercellular space. CLDN4 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the claudin family. Protein type: Membrane protein, integral; Cytoskeletal; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 7q11.23. Cellular Component: tight junction; apicolateral plasma membrane; integral to plasma membrane; apical plasma membrane; plasma membrane; basal plasma membrane; lateral plasma membrane. Molecular Function: identical protein binding; transmembrane receptor activity; structural molecule activity. Biological Process: female pregnancy; signal transduction; response to progesterone stimulus; calcium-independent cell-cell adhesion
尺寸1 :
0.03毫升
价格1 :
155美元
尺寸2 :
0.1毫升
价格2 :
220
size3 :
0.2毫升
价格3 :
295
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。