抗体

Anti-CD35 Antibody-FITC labled

MBS8209536

50 Assays

215美元

单克隆

小鼠

异硫氰酸荧光素

免疫细胞化学, 流式细胞仪, 流式细胞仪

抗体

Anti-CD35 Antibody-FITC labled

[CD35]

[C3BR;1型补体受体;C3b/C4b受体;CD抗原CD35]

[complement receptor type 1 isoform F; Complement receptor type 1; complement receptor type 1; complement component (3b/4b) receptor 1 (Knops blood group); C3b/C4b receptor; CD_antigen: CD35]

[CR1]

[CR1;CR1;KN;C3BR;C4BR;CD35;C3BR]

CR1_HUMAN

单克隆

IgG1

小鼠

人类

2039

Recognises human CD35.

The antibody was purified by affinity chromatography.

液体PBS, pH值7.3, 0.2% BSA, 和0.02% 叠氮化钠

Shipped and store at 4 degree C for one year. Do not freeze.

Immunofluoresence (IF), Flow Cytometry (FC/FACS)

流式细胞仪(FC/流式细胞仪)

Conjugation: FITC

Directions for Use: 1. Take 100 ul peripheral blood anticoagulated by EDTA and add to the bottom of 5 ml tube. 2. Add 10 ul labeled antibody to the bottom of flow tube mixing with the whole blood, incubate for 20 minutes at room temperature away from light. 3. Add 2 ml RBC lysis buffer, incubate for 10 minutes away from light after mixing, dissolve red blood cells. 4. Sample tube is set to 1000 rpm centrifugation for 5 minutes, discard the supernatant. 5. Add 2 ml PBS wash buffer to resuspend the cells, then 1000 rpm centrifugation for 5 minutes, discard the supernatant.

小鼠单克隆抗体CD35(异硫氰酸荧光素)

86793036

NP_000564.2

NM_000573.3

P17927

223,663 Da

Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (1269241); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Immune System Pathway (1269170); Innate Immune System Pathway (1269203); Legionellosis Pathway (469200); Legionellosis Pathway (469186)

This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants, encoding different isoforms, have been characterized. Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized. [provided by RefSeq, Jul 2008]

CR1: Mediates cellular binding of particles and immune complexes that have activated complement. Belongs to the receptors of complement activation (RCA) family. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1q32. Cellular Component: cell surface; integral to plasma membrane; plasma membrane. Molecular Function: complement component C3b receptor activity; complement component C4b binding; complement component C4b receptor activity; complement component C3b binding. Biological Process: negative regulation of complement activation, alternative pathway; complement receptor mediated signaling pathway; negative regulation of complement activation, classical pathway; regulation of complement activation; innate immune response; complement activation, classical pathway. Disease: Knops Blood Group System; Malaria, Susceptibility To

50 Assays

215美元

100 Assays

280