产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗CD279抗体
目录 :
MBS821930
规格 :
0.03毫升
价格 :
155美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
图像
图像 1 :
Western blot analysis of CD279 expression in THP1 (A), HepG2 (B), mouse liver (C), H9C2 (D) whole cell lysates.
产品信息
目录号 :
MBS821930
产品类型 :
抗体
产品全称 :
抗CD279抗体
产品简称 :
[CD279]
产品名称同义词 :
[PD1; Programmed cell death protein 1; Protein PD-1; hPD-1; CD279]
其他名称 :
[programmed cell death protein 1; Programmed cell death protein 1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2; programmed cell death 1; CD_antigen: CD279]
产品基因名称 :
[PDCD1]
其他基因名称 :
[PDCD1;PDCD1;PD1;PD-1;CD279;SLEB2;hPD-1;hPD-l;hSLE1;PD1;蛋白PD-1;hPD-1]
UniProt数据库进入名 :
PDCD1_HUMAN
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
288
特异性 :
Recognizes endogenous levels of CD279 protein.
纯度 :
The antibody was purified by immunogen affinity chromatography.
形式 :
液体0.42% 钾磷酸盐, 0.87% 氯化钠, pH值7.3, 30% 甘油, 和0.01% 叠氮化钠
储存稳定性 :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹)
应用笔记 :
免疫印迹(1/500 - 1/1000)
image1头 :
免疫印迹(免疫印迹)
其它信息1 :
Source: Rabbit
其他信息2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD279. The exact sequence is proprietary.
产品描述 :
兔多克隆抗体CD279
NCBI GI登录号 :
167857792
NCBI登录号 :
NP_005009.2
NCBI基因登录号 :
NM_005018.2
UniProt数据库登录号 :
Q15116
NCBI分子量 :
31,647 Da
NCBI信号通路 :
Adaptive Immune System Pathway (366160); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Costimulation By The CD28 Family Pathway (119552); Immune System Pathway (106386); PD-1 Signaling Pathway (119557); T Cell Receptor Signaling Pathway (83080); T Cell Receptor Signaling Pathway (491)
NCBI总结 :
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse exhausted T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells. Protein type: Apoptosis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q37.3. Cellular Component: plasma membrane; integral to membrane; external side of plasma membrane. Molecular Function: protein binding; signal transducer activity. Biological Process: apoptosis; multicellular organismal development; T cell costimulation; signal transduction; humoral immune response. Disease: Systemic Lupus Erythematosus
尺寸1 :
0.03毫升
价格1 :
155美元
尺寸2 :
0.1毫升
价格2 :
220
size3 :
0.2毫升
价格3 :
295
更多信息或购买 :
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。