抗体

抗IL-1乙抗体

MBS8242899

0.03毫升

155美元

多克隆

unidentified

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化

抗体

抗IL-1乙抗体

[IL-1乙]

[IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin]

[Interleukin-1 beta; Interleukin-1 beta; interleukin-1 beta; interleukin 1 beta; Catabolin]

[IL1B]

[IL1B;IL1B;IL-1;IL1F2;IL1-乙;IL1F2;IL-1乙]

IL1B_HUMAN

多克隆

未知

Human, Mouse, Rat, Rabbit, Monkey

269

Recognizes endogenous levels of IL-1 beta protein.

The antibody was purified by immunogen affinity chromatography.

液体0.42% 钾磷酸盐, 0.87% 氯化钠, pH值7.3, 30% 甘油, 和0.01% 叠氮化钠

Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

免疫印迹, 免疫组化

WB:(1/500 - 1/1000)。 IH:(1/100 - 1/200)

免疫印迹(免疫印迹)

免疫组化(免疫组化)

Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IL-1 beta. The exact sequence is proprietary.

兔多克隆抗体IL-1乙

62906858

P01584.2

P01584

AGE-RAGE Signaling Pathway In Diabetic Complications (1319988); AGE-RAGE Signaling Pathway In Diabetic Complications (1319775); African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Apoptosis Pathway (83060)

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

IL1B: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Monomer. Belongs to the IL-1 family. Protein type: Cytokine. Chromosomal Location of Human Ortholog: 2q14. Cellular Component: autophagic vacuole; cytosol; extracellular region; extracellular space; lysosome; secretory granule. Molecular Function: cytokine activity; interleukin-1 receptor binding; protein domain specific binding. Biological Process: activation of MAPK activity; activation of NF-kappaB transcription factor; aging; apoptosis; cell-cell signaling; chronic inflammatory response to antigenic stimulus; cytokine and chemokine mediated signaling pathway; elevation of cytosolic calcium ion concentration; embryo implantation; estrogen metabolic process; fever; germ cell programmed cell death; glycoprotein metabolic process; hyaluronan biosynthetic process; inflammatory response; inflammatory response to antigenic stimulus; innate immune response; interleukin-1 beta production; lipopolysaccharide-mediated signaling pathway; MAPKKK cascade; memory; negative regulation of cell proliferation; negative regulation of glutamate secretion; negative regulation of insulin receptor signaling pathway; negative regulation of lipid catabolic process; negative regulation of lipid metabolic process; negative regulation of MAP kinase activity; negative regulation of neuron differentiation; negative regulation of transcription from RNA polymerase II promoter; neutrophil chemotaxis; ovulation; pentacyclic triterpenoid metabolic process; polyketide metabolic process; positive regulation of angiogenesis; positive regulation of apoptosis; positive regulation of astrocyte differentiation; positive regulation of chemokine biosynthetic process; positive regulation of fever; positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of heterotypic cell-cell adhesion; positive regulation of histone acetylation; positive regulation of histone phosphorylation; positive regulation of immature T cell proliferation in the thymus; positive regulation of interferon-gamma production; positive regulation of interleukin-2 biosynthetic process; positive regulation of interleukin-6 biosynthetic process; positive regulation of interleukin-6 production; positive regulation of interleukin-8 production; positive regulation of JNK activity; positive regulation of lipid catabolic process; positive regulation of membrane protein ectodomain proteolysis; positive regulation of mitosis; positive regulation of NF-kappaB import into nucleus; positive regulation of nitric oxide biosynthetic process; positive regulation of phagocytosis; positive regulation of prostaglandin secretion; positive regulation of protein amino acid phosphorylation; positive regulation of protein export from nucleus; positive regulation of T cell mediated immunity; positive regulation of T cell proliferation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of vascular endothelial growth factor receptor signaling pathway; protein kinase B signaling cascade; purine base metabolic process; regulation of I-kappaB kinase/NF-kappaB cascade; regulation of insulin secretion; regulation of nitric-oxide synthase activity; response to ATP; response to estradiol stimulus; response to ethanol; response to gamma radiation; response to heat; response to hypoxia; response to L-ascorbic acid; response to morphine; response to ozone; response to peptide hormone stimulus; response to vitamin D; sequestering of triacylglycerol; signal transduction; smooth muscle adaptation; social behavior; stimulatory C-type lectin receptor signaling pathway; wound healing. Disease: Gastric Cancer, Hereditary Diffuse

0.03毫升

155美元

0.1毫升

220

0.2毫升

295