产品简要
公司名称 :
MyBioSource
产品类型 :
抗体
产品名称 :
抗甲1D肾上腺素受体抗体
目录 :
MBS8248057
规格 :
0.03毫升
价格 :
155美元
克隆性 :
多克隆
宿主 :
unidentified
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
MyBioSource 产品网页
图像
图像 1 :
MyBioSource MBS8248057 图像 1
Western blot analysis of Alpha-1D Adrenergic Receptor expression in MCF7 (A), RAW264.7 (B), H9C2 (C) whole cell lysates.
图像 2 :
MyBioSource MBS8248057 图像 2
Immunohistochemical analysis of Alpha-1D Adrenergic Receptor staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
图像 3 :
MyBioSource MBS8248057 图像 3
Immunofluorescent analysis of Alpha-1D Adrenergic Receptor staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
产品信息
目录号 :
MBS8248057
产品类型 :
抗体
产品全称 :
抗甲1D肾上腺素受体抗体
产品简称 :
[甲1D肾上腺素受体]
产品名称同义词 :
[ADRA1A; Alpha-1D adrenergic receptor; Alpha-1A adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor; Alpha-adrenergic receptor 1a]
其他名称 :
[alpha-1D adrenergic receptor; Alpha-1D adrenergic receptor; alpha-1D adrenergic receptor; adrenoceptor alpha 1D; Alpha-1A adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor; Alpha-adrenergic receptor 1a]
产品基因名称 :
[ADRA1D]
其他基因名称 :
[ADRA1D; ADRA1D; DAR; ADRA1; ADRA1A; ADRA1R; ALPHA1; dJ779E11.2; ADRA1A; Alpha-1D adrenoceptor]
UniProt数据库进入名 :
ADA1D_HUMAN
克隆性 :
多克隆
宿主 :
未知
反应物种 :
人类, 小鼠, 大鼠
序列长度 :
572
特异性 :
Recognizes endogenous levels of Alpha-1D Adrenergic Receptor protein.
纯度 :
The antibody was purified by affinity chromatography.
形式 :
液体0.42% 钾磷酸盐, 0.87% 氯化钠, pH值7.3, 30% 甘油, 和0.01% 叠氮化钠
储存稳定性 :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
检测过的应用 :
免疫印迹(免疫印迹), 免疫组化(免疫组化), 免疫荧光(IF), 免疫细胞化学(免疫细胞化学)
应用笔记 :
WB: 1/500 - 1/2000。 IHC: 1/50 - 1/200。 IF/ICC: 1/50 - 1/100
image1头 :
免疫印迹(免疫印迹)
image2头 :
免疫组化(免疫组化)
image3头 :
免疫荧光(IF)
其它信息1 :
Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Alpha-1D Adrenergic Receptor. The exact sequence is proprietary.
产品描述 :
兔多克隆抗体甲1D肾上腺素受体
NCBI GI登录号 :
4501957
NCBI登录号 :
NP_000669.1
NCBI基因登录号 :
NM_000678.3
UniProt数据库登录号 :
P25100
NCBI分子量 :
60,463 Da
NCBI信号通路 :
Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Adrenoceptors Pathway (1269555); Amine Ligand-binding Receptors Pathway (1269553); Calcium Regulation In The Cardiac Cell Pathway (198906); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (12/13) Signalling Events Pathway (1269579); G Alpha (q) Signalling Events Pathway (1269578)
NCBI总结 :
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008]
UniProt数据库总结 :
ADRA1D: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily. Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding. Biological Process: cell proliferation; cell-cell signaling; DNA metabolic process; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); multicellular organismal development; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; positive regulation of cell proliferation; positive regulation of smooth muscle contraction; positive regulation of vasoconstriction
尺寸1 :
0.03毫升
价格1 :
155美元
尺寸2 :
0.1毫升
价格2 :
220
size3 :
0.2毫升
价格3 :
295
更多信息或购买 :
MyBioSource 产品网页
公司信息
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华，公司愿景是“生物研究试剂的源头”，现在位于圣地亚哥市。